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Serotonin/Dopamine Antagonism of Cocaine Effect: 2 - 2

2015-06-08 01:08:49 | BioPortfolio

Published on BioPortfolio: 2015-06-08T01:08:49-0400

Clinical Trials [984 Associated Clinical Trials listed on BioPortfolio]

Infusion Laboratory: Protocol 3 (Risperidone) - 4

The purpose of this study is to evaluate clinical safety issues pertaining to risperidone, to cocaine and to its interaction, and to determine how pretreatment with risperidone modifies th...

Early Phase II Trials for Cocaine Medication Development - 1

The purpose of this study is to develop models for early Phase II testing of potential medications for cocaine dependence: amoxapine, risperidone and other agents. The study was a control...

Risperidone for Treatment of Cocaine Dependence in Outpatients - 12

The purpose of this study is to evaluate pharmacological efficacy and clinical safety of risperidone in the treatment of cocaine and amphetamine dependence.

Serotonin/Dopamine Antagonism of Cocaine Effect: 1 - 1

The purpose of this study is to evaluate use of risperidone with cocaine abusers. Study measures incorporate an appropriate integration of behavioral and neurobiological indices.

Risperidone for the Treatment of Cocaine Dependence - 7

The purpose of this study is to evaluate clinical safety and pharmacological efficacy in the treatment of cocaine dependence, to evaluate impact of treatment on craving, and to correlate e...

PubMed Articles [13811 Associated PubMed Articles listed on BioPortfolio]

Cocaine-induced multifocal leukoencephalopathy mimicking Balo's concentric sclerosis: A 2-year follow-up with serial imaging of a single patient.

Cocaine abuse may cause stroke, metabolic or multifocal inflammatory leukoencephalopathy. We described a patient with cocaine abuse who presented with Balo's type acute multifocal leukoencephalopathy....

Examining the Association Between Psychiatric Disorders and Cocaine Binges: Results From the COSMO Study.

Although cocaine binges and mental health problems have both been identified as significant risk factors for different health hazards, little is known about the relationship between mental health and ...

Structure-Activity Relationship Studies on a Series of 3α-Bis(4-fluorophenyl)methoxytropanes and 3α-Bis(4-fluorophenyl)methylaminotropanes As Novel Atypical Dopamine Transporter (DAT) Inhibitors for the Treatment of Cocaine Use Disorders.

The development of medications to treat cocaine use disorders has thus far defied success, leaving this patient population without pharmacotherapeutic options. As the dopamine transporter (DAT) plays ...

Trends and correlates of cocaine use and cocaine use disorder in the United States from 2011 to 2015.

Recent epidemiological data suggest a resurgence in cocaine use (CU) and cocaine-related problems in the United States. Demographic trends and correlates of problem CU are needed to determine potentia...

Relevance of treated cocaine users' retrospective memory of first cocaine use.

Little is known regarding between-subject variability in the subjective effects of first cocaine use. This study retrospectively assesses the subjective effects of first cocaine use in 160 current tre...

Medical and Biotech [MESH] Definitions

Disorders related or resulting from use of cocaine.

These disorders are related to both SCHIZOPHRENIA SPECTRUM AND RELATED DISORDERS and DEPRESSIVE DISORDERS in terms of symptomatology, family history, and genetics. (DSM-V) .

The purified, alkaloidal, extra-potent form of cocaine. It is smoked (free-based), injected intravenously, and orally ingested. Use of crack results in alterations in function of the cardiovascular system, the autonomic nervous system, the central nervous system, and the gastrointestinal system. The slang term "crack" was derived from the crackling sound made upon igniting of this form of cocaine for smoking.

Disorders related to substance abuse, the side effects of a medication, toxin exposure, and ALCOHOL-RELATED DISORDERS.

Disorders related or resulting from abuse or mis-use of opioids.

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