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Cold Water Immersion Modulates Reinforcing Effects of Nitrous Oxide - 2

2014-08-27 04:00:15 | BioPortfolio

Summary

The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. Comparisons between nitrous oxide, opiates, and benzodiazepine antagonists will be made. To evaluate: cold water immersion modulates the reinforcing effects of nitrous oxide in healthy volunteers.

Study Design

Primary Purpose: Treatment

Conditions

Opioid-Related Disorders

Intervention

Nitrous oxide

Location

University of Chicago, Anesthesia & Critical Care
Chicago
Illinois
United States
60637

Status

Completed

Source

National Institute on Drug Abuse (NIDA)

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T04:00:15-0400

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PubMed Articles [16839 Associated PubMed Articles listed on BioPortfolio]

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Medical and Biotech [MESH] Definitions

Disorders related or resulting from abuse or mis-use of opioids.

Nitrogen oxide (N2O). A colorless, odorless gas that is used as an anesthetic and analgesic. High concentrations cause a narcotic effect and may replace oxygen, causing death by asphyxia. It is also used as a food aerosol in the preparation of whipping cream.

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A neuropathy due to VITAMIN B 12 DEFICIENCY or to excessive NITROUS OXIDE inhalation. It is associated with overproduction of the myelinolytic TUMOR NECROSIS FACTOR-ALPHA.

Disorders related to substance abuse, the side effects of a medication, toxin exposure, and ALCOHOL-RELATED DISORDERS.

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