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Cold Water Immersion Modulates Reinforcing Effects of Nitrous Oxide - 2

2014-08-27 04:00:15 | BioPortfolio

Summary

The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. Comparisons between nitrous oxide, opiates, and benzodiazepine antagonists will be made. To evaluate: cold water immersion modulates the reinforcing effects of nitrous oxide in healthy volunteers.

Study Design

Primary Purpose: Treatment

Conditions

Opioid-Related Disorders

Intervention

Nitrous oxide

Location

University of Chicago, Anesthesia & Critical Care
Chicago
Illinois
United States
60637

Status

Completed

Source

National Institute on Drug Abuse (NIDA)

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T04:00:15-0400

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PubMed Articles [17203 Associated PubMed Articles listed on BioPortfolio]

Upper aerodigestive tract frostbite from inhalation of automotive nitrous oxide.

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Neuropsychiatric Symptoms Induced by Large Doses of Nitrous Oxide Inhalation: A Case Report.

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Medical and Biotech [MESH] Definitions

Disorders related or resulting from abuse or mis-use of opioids.

Nitrogen oxide (N2O). A colorless, odorless gas that is used as an anesthetic and analgesic. High concentrations cause a narcotic effect and may replace oxygen, causing death by asphyxia. It is also used as a food aerosol in the preparation of whipping cream.

These disorders are related to both SCHIZOPHRENIA SPECTRUM AND RELATED DISORDERS and DEPRESSIVE DISORDERS in terms of symptomatology, family history, and genetics. (DSM-V) .

A neuropathy due to VITAMIN B 12 DEFICIENCY or to excessive NITROUS OXIDE inhalation. It is associated with overproduction of the myelinolytic TUMOR NECROSIS FACTOR-ALPHA.

Disorders related to substance abuse, the side effects of a medication, toxin exposure, and ALCOHOL-RELATED DISORDERS.

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