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Clinical Rescue Protocol - 2

2014-08-27 04:00:15 | BioPortfolio

Summary

The purpose of this study is to detect increasing medication dose results in heroin cessation for patients still using, to determine if decreasing medication dose in patients unable to tolerate medication dose increases retention, and to determine if blood levels of methadone or buprenorphine correlate with clinical response.

Study Design

Masking: Double-Blind, Primary Purpose: Treatment

Conditions

Opioid-Related Disorders

Intervention

Buprenorphine

Location

Friends Research Institute
Los Angeles
California
United States
90025

Status

Completed

Source

National Institute on Drug Abuse (NIDA)

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T04:00:15-0400

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Medical and Biotech [MESH] Definitions

A derivative of the opioid alkaloid THEBAINE that is a more potent and longer lasting analgesic than MORPHINE. It appears to act as a partial agonist at mu and kappa opioid receptors and as an antagonist at delta receptors. The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use.

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