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An Open-Label Study of Two Formulations of LX1033 in Healthy Human Subjects

2014-08-27 04:00:28 | BioPortfolio

Summary

The purpose of this study is to assess the pharmacodynamic effects, pharmacokinetics, and safety of two oral formulations (tablet and capsule) of LX1033 in normal healthy volunteers.

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Irritable Bowel Syndrome

Intervention

250 mg capsule, 250 mg tablets

Location

Lexicon Investigational Site
Overland Park
Kansas
United States
66211

Status

Completed

Source

Lexicon Pharmaceuticals

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T04:00:28-0400

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Medical and Biotech [MESH] Definitions

Chronic or recurrent colonic disorders without an identifiable structural or biochemical explanation. The widely recognized IRRITABLE BOWEL SYNDROME falls into this category.

A disorder with chronic or recurrent colonic symptoms without a clearcut etiology. This condition is characterized by chronic or recurrent ABDOMINAL PAIN, bloating, MUCUS in FECES, and an erratic disturbance of DEFECATION.

A subspecies of Bifidobacterium longum that occurs in the GASTROINTESTINAL TRACT of human infants and is used as a PROBIOTIC. It may also be used in the treatment of IRRITABLE BOWEL SYNDROME.

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