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Skin Safety Study to Evaluate the Irritation Potential in Healthy Volunteers

2015-04-08 09:24:21 | BioPortfolio

Published on BioPortfolio: 2015-04-08T09:24:21-0400

Clinical Trials [1581 Associated Clinical Trials listed on BioPortfolio]

Skin Safety Study to Evaluate the Sensitizing Potential in Healthy Volunteers

This is a single center, randomized, controlled, within subject comparison, multiple dose study to determine the sensitization potential of M518101 on normal skin under occlusive patch con...

Study to Investigate the Efficacy and the Safety of M518101 in Psoriasis Patients

This study is to investigate the efficacy and safety of M518101 in male and female plaque psoriasis patients with refractory plaques.

A Repeat Insult Patch Test (RIPT) Study Evaluating the Sensitization Potential of Topical SM04755 Solution in Healthy Volunteers

This is a single center, randomized, controlled, within subject comparison, single dose study to determine the sensitization potential of SM04755 solution on normal skin under semi-occlusi...

Study to Evaluate the Safety and Preliminary Efficacy of IDCT, a Treatment for Symptomatic Lumbar Intervertebral Disc Degeneration

The purpose of this study is to compare the safety and preliminary efficacy of intradiscal injections of two doses of IDCT (Discogenic Cells + Sodium Hyaluronate vehicle) and two controls ...

Cumulative Irritation Test

The purpose of this study is to determine the cumulative irritation potential of the products listed by the Sponsor.

PubMed Articles [7943 Associated PubMed Articles listed on BioPortfolio]

Decellularized Rat Lung Scaffolds Using Sodium Lauryl Ether Sulfate for Tissue Engineering.

Perfusion decellularization with detergents is effective to maintain the architecture and proteins of extracellular matrix (ECM) for use in the field of lung tissue engineering (LTE). However, it is u...

Therapeutic effects of rutaecarpine on dextran sodium sulfate-induced experimental colitis in mice.

To determine the therapic effects of rutaecarpine in dextran sodium sulfate (DSS)induced experimental colitis and explore whether the protective role of rutaecarpine is related to the synthesis and re...

Investigation on the interaction of catalase with sodium lauryl sulfonate and the underlying mechanisms.

As a classic type of anionic surfactants, sodium lauryl sulfonate (SLS) might change the structure and function of antioxidant enzyme catalase (CAT) through their direct interactions. However, the und...

Switchable Photoacoustic Intensity of Methylene Blue via Sodium Dodecyl Sulfate Micellization.

The interaction between methylene blue (MB) and sodium dodecyl sulfate (SDS) has been widely studied spectroscopically, but details about their interactions are limited. Here, we combined photoacousti...

Superabsorbent hydrogel based on sulfonated-starch for improving water and saline absorbency.

The agriculture sectors in many developing countries have been suffering from water shortage and decreasing crop yields. Thus, an increasing interest has been emerged to develop much-needed solutions ...

Medical and Biotech [MESH] Definitions

An anionic surfactant, usually a mixture of sodium alkyl sulfates, mainly the lauryl; lowers surface tension of aqueous solutions; used as fat emulsifier, wetting agent, detergent in cosmetics, pharmaceuticals and toothpastes; also as research tool in protein biochemistry.

A pharmaceutical preparation containing a mixture of water-soluble, conjugated estrogens derived wholly or in part from URINE of pregnant mares or synthetically from ESTRONE and EQUILIN. It contains a sodium-salt mixture of estrone sulfate (52-62%) and equilin sulfate (22-30%) with a total of the two between 80-88%. Other concomitant conjugates include 17-alpha-dihydroequilin, 17-alpha-estradiol, and 17-beta-dihydroequilin. The potency of the preparation is expressed in terms of an equivalent quantity of sodium estrone sulfate.

Derivatives of chondroitin which have a sulfate moiety esterified to the galactosamine moiety of chondroitin. Chondroitin sulfate A, or chondroitin 4-sulfate, and chondroitin sulfate C, or chondroitin 6-sulfate, have the sulfate esterified in the 4- and 6-positions, respectively. Chondroitin sulfate B (beta heparin; DERMATAN SULFATE) is a misnomer and this compound is not a true chondroitin sulfate.

An enzyme that catalyzes the activation of sulfate ions by ATP to form adenosine-5'-phosphosulfate and pyrophosphate. This reaction constitutes the first enzymatic step in sulfate utilization following the uptake of sulfate. EC 2.7.7.4.

Water from natural sources which contain significant concentrations of dissolved salts such as sodium chloride.

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