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Proton w/FOLFIRINOX-Losartan for Pancreatic Cancer

2014-10-05 17:25:34 | BioPortfolio

Published on BioPortfolio: 2014-10-05T17:25:34-0400

Clinical Trials [4021 Associated Clinical Trials listed on BioPortfolio]

Losartan and Nivolumab in Combination With FOLFIRINOX and SBRT in Localized Pancreatic Cancer

This research study is studying a combination of interventions as a possible treatment for pancreatic tumor. The interventions involved in this study are: - FOLFIRINOX which is ...

Proton Beam Irradiation for the Treatment of Unresectable Hepatocellular Cancer or Hepatic Metastases

The main purpose of this study is to determine if high doses of radiation using proton beam can be given safely with low and acceptable side effects. We will also gather information to de...

Proton Beam Radiation Therapy for Early Stage Adenocarcinoma of the Prostate

The primary purpose of this study is to determine if high doses of radiation using proton beam can be given safely with low and acceptable side effects. This study will also gather data t...

Neoadjuvant Accelerated Short Course Radiation Therapy With Proton Beam and Capecitabine for Resectable Pancreatic Cancer

A standard treatment for pancreatic cancer is radiation therapy plus chemotherapy after surgery. Radiation therapy and chemotherapy are commonly given for up to six weeks. Previous researc...

Proton Beam Radiotherapy for Medulloblastoma and Pineoblastoma

There are two types of external radiation treatments (proton beam and photon beam). As part of the participant's treatment, they will receive radiation to the entire central nervous syste...

PubMed Articles [17435 Associated PubMed Articles listed on BioPortfolio]

Population pharmacokinetics of FOLFIRINOX: a review of studies and parameters.

FOLFIRINOX regimen is commonly used in colorectal and more recently pancreatic cancer. However, FOLFIRINOX induces significant and dose-limiting toxic effects leading to empirical dose reduction and s...

Novel models for prediction of benefit and toxicity with FOLFIRINOX treatment of pancreatic cancer using clinically available parameters.

Despite modern chemotherapy regimens, survival of pancreatic cancer patients remains dismal. Toxicity is a major concern and it is a challenge to upfront identify patients with the highest benefit fro...

Association between proton pump inhibitor use and the risk of pancreatic cancer: A Korean nationwide cohort study.

Proton pump inhibitor (PPI) therapy causes hypergastrinemia, which could promote the development and progression of pancreatic cancer. Accordingly, this study aimed to investigate the association betw...

Towards a novel dosimetry system using acrylic disk radiation sensor for proton pencil beam scanning.

Fabricate an acrylic disk radiation sensor (ADRS) and characterize the photoluminescence signal generated from the optical device as basis for the development and evaluation of a new dosimetry system ...

Long-term Outcomes of Globe-Preserving Surgery with Proton Beam Radiation for Adenoid Cystic Carcinoma of the Lacrimal Gland.

To describe outcomes of globe-preserving surgery combined with high dose proton beam radiation (PBR) in treating primary adenoid cystic carcinoma (ACC) of the lacrimal gland.

Medical and Biotech [MESH] Definitions

An optical source that emits photons in a coherent beam. Light Amplification by Stimulated Emission of Radiation (LASER) is brought about using devices that transform light of varying frequencies into a single intense, nearly nondivergent beam of monochromatic radiation. Lasers operate in the infrared, visible, ultraviolet, or X-ray regions of the spectrum.

The use of an external beam of PROTONS as radiotherapy.

Computed tomography modalities which use a cone or pyramid-shaped beam of radiation.

The use of pre-treatment imaging modalities to position the patient, delineate the target, and align the beam of radiation to achieve optimal accuracy and reduce radiation damage to surrounding non-target tissues.

Timing the acquisition of imaging data to specific points in the breathing cycle to minimize image blurring and other motion artifacts. The images are used diagnostically and also interventionally to coordinate radiation treatment beam on/off cycles to protect healthy tissues when they move into the beam field during different times in the breathing cycle.

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