The Effects of tDCS Combined With Balance Training on Postural Control and Spasticity in Chronic Stroke Patients

2015-05-28 22:37:29 | BioPortfolio



Balance impairment and falling negatively impact function of stroke patients. These can be addressed through a tDCS intervention.

Objective:Evaluation of effectiveness of anodal tDCS intervention in adults who have suffered a single first ever stroke using the following essential treatment components; a) active tDCS stimulation paired with Biodex balance training, b)sham tDCS paired with Biodex balance training program.

To identify combinations effects of tDCS stimulation plus balance training . Hypothesis:Anodal tDCS targeting leg motor area (CZ) for 5-days plus Biodex balance training, will significantly improve stroke clients' balance and functional mobility.

Condition Intervention

Sequelae of Stroke Hemiplegic Biodex: Blance training randomized for sham/tDCS stimulation Arms Assigned Interventions

Experimental: Arm 1

tDCS brain stimulation and simultaneous balance training

Participants underwent Active tDCS brain stimulation (20 minutes) and simultaneous balance training(10-15 minutes) for 5 consecutive days.

No Intervention: Arm 2 Sham tDCS brain stimulation (20 minutes) and simultaneous balance training

Outcome Measures:

1. Analysis of postural control using linear and nonlinear methods,in the structure of the time series of the COP Using Approximate entropy,Functional assessment with Berg Balance scale.

2. Spasticity Outcome measurement: Using modified Ashworth scale and H-reflex


Participants underwent tDCS(2mA) brain stimulation (20 minutes) and simultaneous balance training(10-15 minutes) for 5 consecutive days, will be assessed 1 week after the end of intervention.

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment


Ischemic Stroke


Trance cranial direct current stimulation (tDCS), Sham


ShahidBeheshti Univesity of Medical sciences
Iran, Islamic Republic of




Shahid Beheshti Medical University

Results (where available)

View Results


Published on BioPortfolio: 2015-05-28T22:37:29-0400

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Medical and Biotech [MESH] Definitions

A technique of brain electric stimulation therapy which uses constant, low current delivered via ELECTRODES placed on various locations on the scalp.

Application of electric current in treatment without the generation of perceptible heat. It includes electric stimulation of nerves or muscles, passage of current into the body, or use of interrupted current of low intensity to raise the threshold of the skin to pain.

Removal of tissue with electrical current delivered via electrodes positioned at the distal end of a catheter. Energy sources are commonly direct current (DC-shock) or alternating current at radiofrequencies (usually 750 kHz). The technique is used most often to ablate the AV junction and/or accessory pathways in order to interrupt AV conduction and produce AV block in the treatment of various tachyarrhythmias.

The application of repeated, brief periods of vascular occlusion at the onset of REPERFUSION to reduce REPERFUSION INJURY that follows a prolonged ischemic event. The techniques are similar to ISCHEMIC PRECONDITIONING but the time of application is after the ischemic event instead of before.

Ischemic injury to the OPTIC NERVE which usually affects the OPTIC DISK (optic neuropathy, anterior ischemic) and less frequently the retrobulbar portion of the nerve (optic neuropathy, posterior ischemic). The injury results from occlusion of arterial blood supply which may result from TEMPORAL ARTERITIS; ATHEROSCLEROSIS; COLLAGEN DISEASES; EMBOLISM; DIABETES MELLITUS; and other conditions. The disease primarily occurs in the sixth decade or later and presents with the sudden onset of painless and usually severe monocular visual loss. Anterior ischemic optic neuropathy also features optic disk edema with microhemorrhages. The optic disk appears normal in posterior ischemic optic neuropathy. (Glaser, Neuro-Ophthalmology, 2nd ed, p135)

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