Effects of Male-specific Antibodies on Sex Ratio

2014-11-05 01:38:22 | BioPortfolio


Investigation of the ability of antibodies from vasectomized men in binding to Y-spermatozoa as a possible explanation of the lower sex ratio observed after microinsemination using epididymal sperm from vasectomized men.

Study Design

Time Perspective: Prospective


Sperm Antibodies


Antibody-sperm binding


Fertility Clinic, Odense University Hospital




Odense University Hospital

Results (where available)

View Results


Published on BioPortfolio: 2014-11-05T01:38:22-0500

Clinical Trials [1225 Associated Clinical Trials listed on BioPortfolio]

Sperm Capacitation Assay as a Tool to Predict Sperm Potential to Fertilize in IVF Treatment

Our aim is to evaluate the potential of a new laboratory method that measure sperm capacitation to predict fertilization of oocytes in patients that undergo IVF treatments

Fertilizations With Immotile Sperm: Pentoxyphylline Activation Alone, or With Chemical Oocyte Activation

Immotile sperm is a rather frequent problem encountered in IVF patients. Treatment is usually based on inducing motility with pentoxyphylline (PXN) followed by ICSI. However, fertilization...

Split Cohort Trial Comparing IVF Outcomes After the Use of Testicular vs. Ejaculated Sperm for ICSI

The primary objective of this study is to determine if there is a difference in in vitro fertilization (IVF) with intracytoplasmic sperm injection (ICSI) outcomes when using testicular spe...

What is the Best Sperm Source and Way of Sperm Selection in Cases With Abnormal sORP Levels on the Day of ICSI?

Does the level of statistic oxidation reduction potential (sORP) affects the choice of sperm source or sperm selection method used during ICSI.

Magnetic Nanoparticle Sperm Separation for Teratozoospermia Male and Women Older Than 35 Years

Women over 35 years old are likely to suffer from impaired oocyte repair capacity. Teratozoospermia is a condition reflects morphological affection of sperm. These spermatozoa would add an...

PubMed Articles [8648 Associated PubMed Articles listed on BioPortfolio]

The impact of epididymal proteins on sperm function.

The epididymis is necessary for post-testicular sperm maturation as it provides the milieu required for spermatozoa to gain the ability for progressive movement and fertilization. In the epididymis th...

In vitro production of sex preselected cattle embryos using a monoclonal antibody raised against bull sperm epitopes.

Sex preselection has always generated great interest among livestock producers. Among the prevalent sperm sorting methods, there is much evidence that sex sorting has a negative effect on sperm qualit...

The effects of IAM38 blocking or CD4 blocking on the binding of exogenous DNA in rabbit sperm.

The binding of exogenous DNA to sperm is a key process for sperm-mediated gene transfer; however, the underlying molecular mechanisms have yet to be elucidated. In the present study, we aimed to ident...

Sperm can act as vectors for HIV-1 transmission into vaginal and cervical epithelial cells.

Sperm are the major cells in semen. Human sperm possess a number of HIV-1 gp120 binding ligands including sulfogalactosylglycerolipid (SGG). However, the mechanisms of how sperm capture HIV-1 onto the...

Interaction of ouabain and progesterone on induction of bull sperm capacitation.

The endogenous steroid hormone ouabain induces capacitation of bull sperm acting through its receptor Na/K-ATPase on the sperm plasma membrane. Progesterone (P4) is believed to act through the sperm m...

Medical and Biotech [MESH] Definitions

The quality of SEMEN, an indicator of male fertility, can be determined by semen volume, pH, sperm concentration (SPERM COUNT), total sperm number, sperm viability, sperm vigor (SPERM MOTILITY), normal sperm morphology, ACROSOME integrity, and the concentration of WHITE BLOOD CELLS.

An assisted fertilization technique consisting of the microinjection of a single viable sperm into an extracted ovum. It is used principally to overcome low sperm count, low sperm motility, inability of sperm to penetrate the egg, or other conditions related to male infertility (INFERTILITY, MALE).

Interactive processes between the oocyte (OVUM) and the sperm (SPERMATOZOA) including sperm adhesion, ACROSOME REACTION, sperm penetration of the ZONA PELLUCIDA, and events leading to FERTILIZATION.

The structural and functional changes by which SPERMATOZOA become capable of oocyte FERTILIZATION. It normally requires exposing the sperm to the female genital tract for a period of time to bring about increased SPERM MOTILITY and the ACROSOME REACTION before fertilization in the FALLOPIAN TUBES can take place.

The maturing process of SPERMATOZOA after leaving the testicular SEMINIFEROUS TUBULES. Maturation in SPERM MOTILITY and FERTILITY takes place in the EPIDIDYMIS as the sperm migrate from caput epididymis to cauda epididymis.

More From BioPortfolio on "Effects of Male-specific Antibodies on Sex Ratio"

Quick Search


Searches Linking to this Trial