Efficacy of COMB (Comprehensive Behavioral) Model of Treatment of Trichotillomania

2015-02-09 19:23:22 | BioPortfolio


This pilot study is being conducted in order to help make the case for later, more systematic research on the effectiveness of the Comprehensive Behavioral (COMB) model of treating trichotillomania (compulsive hair pulling). The goals are to standardize COMB treatment techniques in the form of a clear written manual for therapists; determine whether therapists can use these guidelines in a consistent manner in making treatment decisions; develop and test the reliability of measures of how well therapists are conducting the treatment; and collect preliminary data on the acceptability of the treatment to patients.

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment






American University
District of Columbia
United States


Active, not recruiting


American University

Results (where available)

View Results


Published on BioPortfolio: 2015-02-09T19:23:22-0500

Clinical Trials [33 Associated Clinical Trials listed on BioPortfolio]

Comprehensive Behavioral (ComB) Model of Treatment for Trichotillomania

This study will be the first randomized controlled trial of Comprehensive Behavior Modification (ComB) as a treatment of trichotillomania (TTM). ComB treatment (12 weekly sessions, followi...

N-Acetylcysteine for Pediatric Trichotillomania

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Testing a New Therapy for Trichotillomania

This study will test the effectiveness of a new behavioral therapy for adults with trichotillomania (compulsive hair pulling).

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The goal of the proposed study is to evaluate the efficacy and safety of dronabinol in trichotillomania. 50 subjects with DSM-5 trichotillomania will receive 6 weeks of double-blind dronab...

Methylphenidate in ADHD With Trichotillomania

This study will evaluate the safety and effectiveness of methylphenidate in treating attention deficit hyperactivity disorder (ADHD) in children with both ADHD and trichotillomania. ...

PubMed Articles [19 Associated PubMed Articles listed on BioPortfolio]

Milk Thistle Treatment for Children and Adults with Trichotillomania: A Double-Blind, Placebo-Controlled, Crossover Negative Study.

Data on the pharmacological treatment of trichotillomania are limited. Milk thistle has antioxidant properties and showed promise in trichotillomania in a prior case report. The goal of the current st...

A Pilot Examination of Oxidative Stress in Trichotillomania.

Trichotillomania is a relatively common illness whose neurobiology is poorly understood. One treatment for adult trichotillomania, n-acetyl cysteine (NAC), has antioxidative properties, as well as eff...

Confirmatory factor analysis of the SLEEP-50 Questionnaire in Trichotillomania (Hair-Pulling Disorder) and Excoriation (Skin-Picking) Disorder.

The study objective was to perform a confirmatory factor analysis of the SLEEP-50 Questionnaire (SLEEP-50) in Trichotillomania (Hair-Pulling Disorder) and Excoriation (Skin-Picking) Disorder and compa...

Trichotillomania: a psychopathological perspective and the psychiatric comorbidity of hair pulling.

Trichotillomania, or hair-pulling disorder, is classified as an obsessive-compulsive spectrum disorder and is seen predominantly in females. This is a non-systematic review article focusing on the psy...

Estimating patient-specific treatment advantages in the 'Treatment for Adolescents with Depression Study'.

The 'Treatment for Adolescents with Depression Study' (TADS,, identifier: NCT00006286) was a cornerstone, randomized controlled trial evaluating the effectiveness of standard treatm...

Medical and Biotech [MESH] Definitions

Compulsion to pull out one's hair.

Fleshy and reddish outgrowth of skin tissue found on top of the head, attached to the sides of the head, and hanging from the mandible of birds such as turkeys and chickens.

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