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Genitourinary and Pharyngeal Pharmacokinetics of Solithromycin

2015-03-25 05:24:23 | BioPortfolio

Published on BioPortfolio: 2015-03-25T05:24:23-0400

Clinical Trials [16 Associated Clinical Trials listed on BioPortfolio]

Rapid Diagnosis of Antibiotic Resistance in Gonorrhoea

The purpose of this study is to develop a laboratory-based assay that will be a real-time PCR test to detect the organism N. gonorrhoeae and its most important genetic markers of antimicro...

A Study to Evaluate the Anti-inflammatory Effects of Solithromycin in Chronic Obstructive Pulmonary Disease

This study examines the potential benefit of a new antibiotic, Solithromycin, for the long-term treatment of Chronic Obstructive Pulmonary Disease (COPD). Solithromycin is hypothesised to ...

Pharmacokinetics and Safety of Solithromycin in Adolescents and Children

Pediatric study to evaluate the safety and pharmacokinetics of solithromycin (oral and intravenous) in children ages 0 to 17

Safety and Efficacy of Solithromycin in the Treatment of Nonalcoholic Steatohepatitis Without Cirrhosis

The purpose of this study is to evaluate the effects of solithromycin on hepatic histology and biomarkers in patients with nonalcoholic steatohepatitis.

A Study to Evaluate the Efficacy and Safety of Oral Solithromycin Compared to Intramuscular Ceftriaxone Plus Oral Azithromycin in the Treatment of Patients With Gonorrhea

This study will compare a single dose of oral solithromycin to the standard of care (intramuscular ceftriaxone plus oral azithromycin) in the treatment of patients with urogenital gonorrhe...

PubMed Articles [13 Associated PubMed Articles listed on BioPortfolio]

We need to consider collateral damage to resistomes when we decide how frequently to screen for chlamydia/gonorrhoea in PrEP cohorts.

Numerous PrEP guidelines recommend 3 monthly screening for gonorrhoea and chlamydia. To quantify the risk of antimicrobial resistance this may induce, we conducted a literature review of the incidence...

Epidemiological, behavioural, and clinical factors associated with antimicrobial-resistant gonorrhoea: a review.

Antimicrobial-resistant is a global public health problem in the 21st century. has developed resistance to all classes of antibiotics used for empirical treatment, and clinical treatment failure cau...

Spatial clusters of gonorrhoea in England with particular reference to the outcome of partner notification: 2012 and 2013.

This study explored spatial-temporal variation in diagnoses of gonorrhoea to identify and quantify endemic areas and clusters in relation to patient characteristics and outcomes of partner notificatio...

Microscopic examination of Gram-stained smears for anogenital gonorrhoea in men who have sex with men is cost-effective: evidence from a modelling study.

To assess the cost-effectiveness of three testing strategies with or without light microscopic Gram-stained smear (GSS) evaluation for the detection of anogenital gonorrhoea among men who have sex wit...

Effect of rectal douching/enema on rectal gonorrhoea and chlamydia among a cohort of men who have sex with men on HIV pre-exposure prophylaxis.

Rectal douching/enema (RD) is a common practice among men who have sex with men (MSM) in preparation for sex. RD can break down the rectal mucosal barrier and potentially affect the rectal microbiome....

Medical and Biotech [MESH] Definitions

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