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Lung Cancer Screening Study With Low-dose CT Scan and Blood Biomarker

2015-03-13 02:53:24 | BioPortfolio

Summary

Lung cancer is the number one cancer killer in the USA. Early stage lung cancer is asymptomatic. Most patients with lung cancer are usually symptomatic at diagnosis and already have advanced stage disease. Low dose CT screening (LDCT) for high risk individuals has recently been shown to decrease lung cancer mortality by 20%. However, 4 out of 5 lung cancer deaths are not prevented with LDCT screening alone.

Description

In this trial, the addition of a blood biomarker test is being combined with early LDCT to determine if screening with combination may result in detection of more lung cancer at an earlier stage of disease.The study will also assess if the blood test is able to detect lung cancers in high risk individuals when the LDCT is negative for cancer. There will be health-economic costs included in the final analysis of study data.

Study Design

Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Screening

Conditions

High Risk of Developing Lung Cancer

Intervention

CT scan & Early CDT Lung test, CT scan & Early CDT Lung test

Location

National Jewish Health
Denver
Colorado
United States
80206

Status

Recruiting

Source

National Jewish Health

Results (where available)

View Results

Links

Published on BioPortfolio: 2015-03-13T02:53:24-0400

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