Impact of Starting a Dolutegravir-based Regimen on HIV-1 Proviral DNA Reservoir Of Treatment Naïve and Experienced Patients

2015-03-26 05:53:22 | BioPortfolio


This is a multi-center prospective study. The primary objective of DRONE study is to investigate the change of the size of HIV-1 DNA reservoir in blood from baseline to week 48 (W48) in participants treated by DTG-based regimen. Secondary objectives include: DTG pharmacokinetic and analysis of biomarkers of immune activation from baseline to W48.

Study Design

Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment


HIV-1 Infection


Blood samples


Centre hospitalier de Belfort-Montbéliard




University Hospital, Strasbourg, France

Results (where available)

View Results


Published on BioPortfolio: 2015-03-26T05:53:22-0400

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