Targeted Levothyroxine Dosing in Infants With Congenital Hypothyroidism

2015-04-10 09:23:22 | BioPortfolio


This is a clinical study comparing targeted levothyroxine dosing based on thyroid anatomy as visualized on ultrasound (normal vs. ectopic/sublingual vs. athyreosis) to empiric levothyroxine dosing in infants with congenital hypothyroidism. Patients enrolled in the study for targeted dosing will be compared to controls obtained by retrospective chart review. The main outcome is to determine if there is a difference in the frequency of over-treatment and under-treatment during the first 6 months of therapy.

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment


Congenital Hypothyroidism


Levothyroxine, Ultrasound


Riley Hospital for Children
United States




Indiana University

Results (where available)

View Results


Published on BioPortfolio: 2015-04-10T09:23:22-0400

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Medical and Biotech [MESH] Definitions

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