Study of Osteopathic Manipulative Medicine on the Autonomic Nervous System

2015-05-11 17:56:23 | BioPortfolio


The purpose this study is to determine which manual medicine technique or combination of techniques has the greatest effect on the natural changes in heart rate.


This study intends to examine how three different OMM techniques, sub-occipital release, rib-raising, and stellate ganglion release, impact autonomic nervous system tone. Subjects will be randomly assigned to one of four cohort groups, receiving either sub-occipital release, rib-raising, stellate ganglion release or all three treatment techniques. A shift towards sympathetic tone will be induced in all subjects using a tilted-to-seated-position test (Tilt-Seated Position test) and cognitive challenge test, consisting of computerized questions that become progressively more difficult, and which subjects are asked to answer as quickly and accurately as possible. These stress tests will be induced twice, once without any OMM treatment and a second time with the designated OMM treatment(s). The sympathetic-dependent response to orthostatic change and cognitive challenges will be determined by Fourier analysis of heart rate variability, recorded using an EKG attached to each subject.

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Factorial Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment


Osteopathic Manual Manipulation of Neurovascular Regulation


Osteopathic Manual Medicine, Sham


New York Institute of Technology College of Osteopathic Medicine Academic Health Care Center
Old Westbury
New York
United States




New York Institute of Technology

Results (where available)

View Results


Published on BioPortfolio: 2015-05-11T17:56:23-0400

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Medical and Biotech [MESH] Definitions

Musculoskeletal manipulation based on the principles of OSTEOPATHIC MEDICINE developed in 1874 by Dr Andrew Taylor Still.

Licensed physicians trained in OSTEOPATHIC MEDICINE. An osteopathic physician, also known as D.O. (Doctor of Osteopathy), is able to perform surgery and prescribe medications.

Hospitals providing care utilizing the generally accepted medical and surgical methods but with emphasis on the osteopathic system of therapy.

The planned and carefully managed manual movement of the musculoskeletal system, extremities, and spine to produce increased motion. The term is sometimes used to denote a precise sequence of movements of a joint to determine the presence of disease or to reduce a dislocation. In the case of fractures, orthopedic manipulation can produce better position and alignment of the fracture. (From Blauvelt & Nelson, A Manual of Orthopaedic Terminology, 5th ed, p264)

An occupational discipline founded by D.D. Palmer in the 1890's based on the relationship of the spine to health and disease. The spine is analyzed by X-rays and palpation, and vertebrae are adjusted manually to relieve pressures on the spinal cord. OSTEOPATHIC MEDICINE was originally similar but has become more like FAMILY PRACTICE.

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