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Studying Gene Expression and Location in Samples From Patients With Brain Tumors

2015-06-05 00:38:23 | BioPortfolio

Summary

RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to brain tumors.

PURPOSE: This research studies gene expression and location in samples from patients with brain tumors.

Description

OBJECTIVES:

- To determine the expression and subcellular localization of nei endonuclease VIII-like 3 (NEIL3) in brain tumors.

OUTLINE: Tissue microarray samples are analyzed for NEIL3 expression and subcellular localization by immunohistochemical methods.

Study Design

Observational Model: Case-Only, Time Perspective: Retrospective

Conditions

Brain and Central Nervous System Tumors

Intervention

gene expression analysis, genetic linkage analysis, microarray analysis, immunohistochemistry staining method, laboratory biomarker analysis

Status

Active, not recruiting

Source

Children's Oncology Group

Results (where available)

View Results

Links

Published on BioPortfolio: 2015-06-05T00:38:23-0400

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