Topics

EMD and/or Bone Substitute for the Treatment of Class II Furcations

2015-06-19 04:23:44 | BioPortfolio

Summary

To clinically evaluate the treatment of mandibular class II furcation defects with enamel matrix derivative (EMD) and/or a bone substitute graft make of beta tricalcium phosphate/hydroxyapatite (βTCP/HA).

Description

To clinically evaluate the treatment of mandibular class II furcation defects with enamel matrix derivative (EMD) and/or a bone substitute graft make of beta tricalcium phosphate/hydroxyapatite (βTCP/HA). Forty-one patients, presenting a mandibular class II buccal furcation defect, probing pocket depth (PPD) ≥ 4 mm and bleeding on probing, will be included. They will be randomly assigned to the groups: 1- EMD (n = 13); 2- βTCP/HA (n = 14); 3- EMD + βTCP/HA (n = 14). Plaque index (PI), gingival index (GI), relative gingival margin position (RGMP), relative vertical and horizontal attachment level (RVCAL and RHCAL) and PPD will be evaluated at baseline and 12 months. The mean horizontal clinical attachment level gain will be considered the primary outcome variable.

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Investigator), Primary Purpose: Treatment

Conditions

Periodontal Disease

Intervention

EMD, βTCP/HA, Flap access surgery

Location

Piracicaba Dental School, State University of Campinas
Piracicaba
São Paulo
Brazil
13414-903

Status

Completed

Source

University of Campinas, Brazil

Results (where available)

View Results

Links

Published on BioPortfolio: 2015-06-19T04:23:44-0400

Clinical Trials [1516 Associated Clinical Trials listed on BioPortfolio]

Periodontal Surgery With Early vs Delayed Endodontic Treatment in Endo-Perio Lesions Without Communication

The aim of this study is to evaluate the periodontal parameters in terms of periodontal healing by periodontal surgical therapy with simultaneous or delayed endodontic therapy in managemen...

Imaging Analysis Following Periodontal Surgery

This is a single centre, randomised, single-blind, parallel-group clinical trial that aims at evaluating the use of imaging (2D and 3D) in obtaining geometric and thermometric changes of p...

The Effect of A-PRF Versus Open Flap Debridement in the Treatment of Patients With Stage III Periodontitis

To assess the effectiveness of advanced PRF as compared to open flap debridement in treatment of periodontal intraosseous defects in stage III periodontitis patients.

Efficacy of Adjunctive Antimicrobial Photodynamic Therapy for Residual Pockets in Previously Surgically Treated Teeth

Traditionally, periodontal gum surgery has been used as a method to gain access to inflamed periodontal pockets around teeth. The outcome of these surgeries, however, is not always success...

Influence of Gingival Biotype on the Outcome of Open Flap Debridement

The influence of periodontal thickness has been documented in outcome of various periodontal interventions like non surgical periodontal therapy, mucogingival therapy, guided tissue regene...

PubMed Articles [27154 Associated PubMed Articles listed on BioPortfolio]

Long-Term (15 to 20 Years) Outcomes of Papillae Preservation Flap Surgery in Esthetic Areas.

Several techniques have been proposed to maintain full papillary form and preserve soft tissue during periodontal surgical access. However, very little evidence of long-term results is available. The ...

Dexmedetomidine as an Alternative Anesthetic Agent for Flap Surgery: An Intravital Evaluation in the Cremaster Muscle Flap.

Flap surgery is one of the most commonly used techniques of reconstructive surgery for effective repair of damaged tissue. Optimal anesthetic technique and anesthetic agent plays an important role in ...

The flip-flap puzzle flap: Another recycling option.

Post-traumatic soft tissue defects sometimes require sequential flap coverage to achieve complete healing. In the era of propeller flaps, which were developed to reduce donor site morbidity, Feng et a...

Developing a periodontal disease antibody array for the prediction of severe periodontal disease using machine learning classifiers.

The aim of this study was to simultaneously and quantitatively assess the expression levels of 20 periodontal disease-related proteins in gingival crevicular fluid (GCF) from normal controls (NOR) and...

WITHDRAWN: Guided tissue regeneration for periodontal infra-bony defects.

Conventional treatment of destructive periodontal (gum) disease arrests the disease but does not usually regain the bone support or connective tissue lost in the disease process. Guided tissue regener...

Medical and Biotech [MESH] Definitions

Any restorative and replacement device that is used as a therapeutic aid in the treatment of periodontal disease. It is an adjunct to other forms of periodontal therapy and does not cure periodontal disease by itself. (Boucher's Clinical Dental Terminology, 3d ed)

Loss or destruction of periodontal tissue caused by periodontitis or other destructive periodontal diseases or by injury during instrumentation. Attachment refers to the periodontal ligament which attaches to the alveolar bone. It has been hypothesized that treatment of the underlying periodontal disease and the seeding of periodontal ligament cells enable the creating of new attachment.

Endonucleases that remove 5' DNA sequences from a DNA structure called a DNA flap. The DNA flap structure occurs in double-stranded DNA containing a single-stranded break where the 5' portion of the downstream strand is too long and overlaps the 3' end of the upstream strand. Flap endonucleases cleave the downstream strand of the overlap flap structure precisely after the first base-paired nucleotide, creating a ligatable nick.

A surgical procedure to correct MYOPIA by CORNEAL STROMA subtraction. It involves the use of a microkeratome to make a lamellar dissection of the CORNEA creating a flap with intact CORNEAL EPITHELIUM. After the flap is lifted, the underlying midstroma is reshaped with an EXCIMER LASER and the flap is returned to its original position.

Surgical dressings, after periodontal surgery, applied to the necks of teeth and the adjacent tissue to cover and protect the surgical wound. (Boucher's Clinical Dental Terminology, 4th ed, p218)

More From BioPortfolio on "EMD and/or Bone Substitute for the Treatment of Class II Furcations"

Quick Search

Relevant Topics

Osteoporosis
Osteoporosis is a disease in which the bones become extremely porous, are subject to fracture, and heal slowly, occurring especially in women following menopause and often leading to curvature of the spine from vertebral collapse. Follow and track&n...

Surgical treatments
Surgery is a technology consisting of a physical intervention on tissues. All forms of surgery are considered invasive procedures; so-called "noninvasive surgery" usually refers to an excision that does not penetrate the structure being exci...

Dentistry
Dentistry is the study, management and treatment of diseases and conditions affecting the mouth, jaw, teeth and their supporting tissues (Oxford Medical Dictionary) The work of a dentist ranges from regular patient check-up to orthodontics and surgery....


Searches Linking to this Trial