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An in Vitro Evaluation of Antimicrobial Photodynamic Therapy on Deciduous Carious Dentin

2015-06-25 05:38:23 | BioPortfolio

Summary

Despite of the decline of dental caries, this disease is still common in polarized groups affecting children. Therefore, the aim of this randomized blind in vivo study was to compare the antimicrobial effect of two antimicrobial therapies in deciduous carious dentin. Thirty two patients aging from 5 to 7 years old had partial caries removal in deep carious dentin lesion in deciduous molar and were divided in three groups: Control - chlorhexidine and resin modified glass ionomer cement (RMGIC); LEDTB - antimicrobial photodynamic therapy (APDT) with LED associated with toluidine blue orto dye solution and RMGIC; LMB - APDT with laser associated with methylene blue dye solution and RMGIC. The patients were submitted to initial clinical and radiographic examination and demographic features were evaluated by biofilm, gingival, and dmft/dmfs indexes, besides clinical and radiographic follow up at 6 and 12 months after the treatments. The carious dentin was collected before and after each treatment and the number of Streptococcus mutans, Streptococcus sobrinus, Lactobacillus casei, Fusobacterium nucleatum, Atopobium rimae and total bacteria were established by quantitative PCR.

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment

Conditions

Dental Caries

Intervention

Rubber dam isolation, Tooth drying, Dentin wash with chlorhexidine 2%, Antimicrobial Photodynamic Therapy 1, Antimicrobial Photodynamic Therapy 2

Status

Completed

Source

University of Sao Paulo

Results (where available)

View Results

Links

Published on BioPortfolio: 2015-06-25T05:38:23-0400

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