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Monitoring Radiation Induced Cardiac Damage by Blood Markers

2015-06-26 06:23:22 | BioPortfolio

Summary

Rationale:

Radiation induced cardiac toxicity after treatment for intrathoracic tumours is a clinically relevant problem. So far, no clinical prediction models exist for cardiac toxicity. In particular, the relationship between radiation dose parameters and the risk of cardiac toxicity remains to be determined.

Clinical prediction models for cardiac toxicity are difficult to obtain, e.g. due to long latency time. Therefore, objective surrogate markers, for cardiac toxicity such as NT pro BNP and hs-TNT, as obtained during and after treatment may be of great value.

Objective:

The main objective to find a correlation between the rise in NT pro BNP level and the radiation dose given to the heart.

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Conditions

Radiation Induced Cardiac Damage

Intervention

Blood sampling

Location

University Medical Center Groningen
Groningen
Netherlands
9700RB

Status

Not yet recruiting

Source

University Medical Centre Groningen

Results (where available)

View Results

Links

Published on BioPortfolio: 2015-06-26T06:23:22-0400

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