Clinical Risk Score Predicting the Cardiac Rupture in Patients With ST-elevation Myocardial Infarction

2015-06-30 07:53:22 | BioPortfolio


The purpose of this study is to validate a practical risk score to predict the mechanical complication of ST-elevation myocardial infarction (STEMI).


STEMI patients chewed 300 mg aspirin and 600 mg clopidogrel in the emergency department, followed by oral 100 mg aspirin and 75mg clopidogrel daily for at least 12 months. STEMI patients received low molecular weight heparin (LMWH), β-blockers, and angiotensin converting enzyme inhibitors (ACEI) or angiotensin receptor blockers (ARB) according to the STEMI guideline, unless there were contraindications to these drugs. Peripheral blood samples were collected from patients within 2 hours of admission for blood routines and blood biochemistry examinations. White blood cell counts and level of hemoglobin were assessed with automated cell counters via standard techniques. The investigators followed up patients in validation group for three month to observe the cardiac rupture events and other adverse cardiac events .

Study Design

Observational Model: Cohort, Time Perspective: Prospective


Cardiac Rupture


Grouping by different risk stratification


Chinese People's Liberation Army General Hospital




Chinese PLA General Hospital

Results (where available)

View Results


Published on BioPortfolio: 2015-06-30T07:53:22-0400

Clinical Trials [1509 Associated Clinical Trials listed on BioPortfolio]

Predictive Risk Stratification Through T Variability in ICD Patients Without Pacing Indications

The aim of the study is to assess the negative predictive value of the T amplitude variance as a method for risk stratification for patients with an increased risk for SCD.

In Vivo Evaluation of Growth and Risk of Rupture of Dilated Ascending Aorta Using 4D Cardiac Magnetic Resonance

Ascending aorta aneurysmal disease is common and can be complicated by dissection or rupture. There is substantial variation in individual aneurysm progression: established risk factors fo...

Optical Coherence Tomography Examination in Myocardial Infarction

Different plaque morphology may have an important effect on the prognosis of acute myocardial infarction (AMI), as recent studies show that patients with plaque rupture have a significantl...

Risk Stratification Using PET in HCM

The overall rationale is to reduce the risk of sudden cardiac death in individuals with hypertrophic cardiomyopathy (HCM). The novel approach of this study is to correlate Positron Emissio...

Cardiac MRI Biomarker Testing (GCC 1618)

This research study can help understand how cardiac changes may occur with radiation therapy to the heart based off measurements obtained through biomarkers and cardiac imaging. Researche...

PubMed Articles [16307 Associated PubMed Articles listed on BioPortfolio]

Combining noninvasive risk stratification parameters improves the prediction of mortality and appropriate ICD shocks.

Sudden cardiac death (SCD) results from a complex interplay of abnormalities in autonomic function, myocardial substrate and vulnerability. We studied whether a combination of noninvasive risk stratif...

Predicting risk of rupture and rupture-preventing reinterventions following endovascular abdominal aortic aneurysm repair.

Clinical and imaging surveillance practices following endovascular aneurysm repair (EVAR) for intact abdominal aortic aneurysm (AAA) vary considerably and compliance with recommended lifelong surveill...

Risk stratification and role for additional diagnostic testing in patients with acute chest pain and normal high-sensitivity cardiac troponin levels.

Normal high sensitivity cardiac troponin (hs-cTn) assays rule out acute myocardial infarction (AMI) with great accuracy, but additional non-invasive testing is frequently ordered. This observational s...

Cardiac Troponin T Risk Stratification Model Predicts All-Cause Mortality Following Kidney Transplant.

We evaluated the role of increased cardiac troponin T (cTnT), vascular, and cardiac diseases in predicting 5 and 10-year all-cause mortality after kidney transplantation.

Abdominal Wall Reconstruction Risk Stratification Tools: A Systematic Review of the Literature.

Ventral hernias are a common pathology encountered by surgeons. Multiple risk stratification tools have been developed in attempts to predict a patient's postoperative risk for complication. The aim o...

Medical and Biotech [MESH] Definitions

Restoration of functions to the maximum degree possible in a person or persons suffering from a CARDIOVASCULAR DISEASE. It also includes cardiac conditioning and SECONDARY PREVENTION in patients with elevated cardiovascular risk profile.

Disease-related laceration or tearing of tissues of the heart, including the free-wall MYOCARDIUM; HEART SEPTUM; PAPILLARY MUSCLES; CHORDAE TENDINEAE; and any of the HEART VALVES. Pathological rupture usually results from myocardial infarction (HEART RUPTURE, POST-INFARCTION).

Laceration or tearing of cardiac tissues appearing after MYOCARDIAL INFARCTION.

Rupture of the SPLEEN due to trauma or disease.

The tearing or bursting of the wall along any portion of the AORTA, such as thoracic or abdominal. It may result from the rupture of an aneurysm or it may be due to TRAUMA.

More From BioPortfolio on "Clinical Risk Score Predicting the Cardiac Rupture in Patients With ST-elevation Myocardial Infarction"

Quick Search


Relevant Topic

Enzymes are proteins that catalyze (i.e., increase the rates of) chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical re...

Searches Linking to this Trial