How Well Does the Data Obtained From Heidelberg Edge Perimeter Visual Field Compare to Standard Octopus Visual Field

2015-08-18 20:08:23 | BioPortfolio


The purpose of this study is to compare standard automated perimetry (SAP) using the Heidelberg Edge Perimeter (HEP) with the Octopus Visual Field (OVF) analyzer and determine test-retest reliability of both parameters in detecting glaucomatous visual field losses.


After obtaining informed consent, each patient will undergo the following tests:

1. Standard ophthalmic examination (usual care): Best-corrected visual acuity testing, slit lamp biomicroscopy, Goldman applanation tonometry, corneal thickness measurement and fundoscopy.

2. G-top strategy using the OVF Analyzer (G-Top, Koeniz, Switzerland). The MD, PSD will be recorded.

3. HEP SAP using the advanced staircase thresholding algorithm (ASTA). This will be performed once. The MD and PSD will be recorded.

4. Spectralis OCT using the GMPE program will be performed once in a non - dilated condition. The RNFL thickness in 6 sectors (SN, ST, IN, IT, N and T) along with the structure-function correlation will be recorded.

The investigators will randomize the order of the HEP SAP III and the OVF, and the order of the eye tested (right vs. left) if both eyes of the patients meet the inclusion criteria. Forty eyes (40) of patients with glaucoma will be randomly chosen from this group and will be asked to return in 3-6 month for retesting HEP and OVF.

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Diagnostic




Heidelberg Edge Perimeter, Octopus Visual Field


Active, not recruiting


Wills Eye

Results (where available)

View Results


Published on BioPortfolio: 2015-08-18T20:08:23-0400

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Partial or complete loss of vision in one half of the visual field(s) of one or both eyes. Subtypes include altitudinal hemianopsia, characterized by a visual defect above or below the horizontal meridian of the visual field. Homonymous hemianopsia refers to a visual defect that affects both eyes equally, and occurs either to the left or right of the midline of the visual field. Binasal hemianopsia consists of loss of vision in the nasal hemifields of both eyes. Bitemporal hemianopsia is the bilateral loss of vision in the temporal fields. Quadrantanopsia refers to loss of vision in one quarter of the visual field in one or both eyes.

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Ophthalmology is the branch of medicine that is devoted to the study and treatment of eye diseases. As well as mild visual defects correctable by lenses, ophthalmology is concerned with glaucoma, uveitis and other serious conditions affecting the eye, ...

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