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In order to examine how the liver heals, we want to use blood samples to check for the occurrence of special liver inflammation cells (CD163 and CD206). To assess to which extent fibrosis disappear during treatment, we want to examine the liver with FibroScan (a type of ultrasound examination) and also preferably with extraction of a small tissue sample. We want to examine how the liver function as inflammation and scar tissue decrease, especially concerning the liver's ability to produce proteins. Furthermore, we want to examine with a gastroscopy, if the circulation of blood in the liver is improved after successful treatment with the expected result that potential varicose veins in the esophagus vanish.
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Galactose, Gastroscopy, Liver biopsy, Fibroscan, Liver vein catheterization, Sofosbuvir
Aarhus University Hospital
University of Aarhus
Published on BioPortfolio: 2015-08-19T20:23:23-0400
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An enzyme that catalyzes the synthesis of UDPgalactose from UTP and galactose-1-phosphate. It is present in low levels in fetal and infant liver, but increases with age, thereby enabling galactosemic infants who survive to develop the capacity to metabolize galactose. EC 188.8.131.52.
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