Advertisement

Topics

Stopping Cavities Study: Diamine Silver Fluoride

2015-08-31 23:23:23 | BioPortfolio

Summary

This study is being conducted to test whether the use of diammine silver fluoride (also called silver diamine fluoride) hardens the cavity sufficiently so that it arrests.

Description

Phase III RCT with two arms: (1) 38% diammine silver fluoride; (2) distilled fluoride free water. Subjects are 200 preschool children in good general health with untreated tooth decay. Intervention is topical application of the study drug to the open cavity. Primary outcome is caries activity at 14-21 days.

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Conditions

Dental Caries

Intervention

38% diammine silver fluoride

Location

Advantage Dental Plans
Redmond
Oregon
United States
97756

Status

Not yet recruiting

Source

Advantage Dental Services, LLC

Results (where available)

View Results

Links

Published on BioPortfolio: 2015-08-31T23:23:23-0400

Clinical Trials [951 Associated Clinical Trials listed on BioPortfolio]

Diammine Silver Fluoride in Arresting Enamel Caries Lesions on Babies' Occlusal Surfaces

This study aims to verify the actual possibility of using silver diammine fluoride (SDF) in arresting enamel caries lesions on occlusal surfaces of primary molars in babies. Besides, the c...

Comparative Effectiveness of Treatments to Prevent Dental Caries

Dental caries (tooth decay) is the most prevalent childhood disease in the world. Multiple interventions are available to treat and prevent caries. The aim of the proposed study is to comp...

Comparative Effectiveness of School-based Caries Prevention

Dental caries (tooth decay) is the most prevalent childhood disease in the world. Multiple interventions are available to treat and prevent caries. The aim of the proposed study is to comp...

Effectiveness on SDF Solution and PVP-I Combined NaF Varnish in Preventing Root Caries in Elders

The main objective of this study is to compare the effectiveness and cost-effectiveness of 4-monthly application of 10% povidone iodine solution followed by 5% sodium fluoride varnish with...

Effectiveness of Silver Diamine Fluoride as a Treatment for Caries in Comparison to Traditional Restorative Techniques

The purpose of this study is to compare standard fillings and silver diamine fluoride (SDF) for treatment of cavities in baby teeth. The investigators will compare the effectiveness of sto...

PubMed Articles [2368 Associated PubMed Articles listed on BioPortfolio]

Silver deposition on demineralized dentine surface dosed by silver diammine fluoride with different saliva.

Silver diammine fluoride (SDF) is an anticaries agent that binds to tooth tissue. The aim of the present study was investigate the dose-response effect of SDF on demineralized dentine in basal medium ...

Comparative cariostatic efficacy of a novel Nano-silver fluoride varnish with 38% silver diamine fluoride varnish a double-blind randomized clinical trial.

To evaluate the clinical cariostatic efficacy of a concocted 5% Nano-silver incorporated Sodium fluoride (NSSF) dental varnish with 38% Silver diamine fluoride (SDF) in preventing the progression of d...

Community trial of silver fluoride treatment for deciduous dentition caries in remote Indigenous communities.

Silver fluoride 40% followed by 10% stannous fluoride (AgF) has been used in dental practice in some parts of Australia for many years. This study compared the effectiveness of application of AgF with...

Effect of silver diamine fluoride and potassium iodide on shear bond strength of glass ionomer cements to caries-affected dentine.

To investigate the effect of silver diamine fluoride (SDF) and potassium iodide (KI) treatment on dentine discolouration and the shear bond strength (SBS) of glass ionomer cements (GICs) to artificial...

The effect of fluoride varnish Duraphat in preventing deciduous dental caries in preschool children.

To evaluate the effect of fluoride varnish Duraphat on preventing caries of primary teeth caries, and provide scientific basis for the establishment of oral health care.

Medical and Biotech [MESH] Definitions

A source of inorganic fluoride which is used topically to prevent dental caries.

Inorganic fluorides of tin. They include both stannic fluoride (tin tetrafluoride) and stannous fluoride (tin difluoride). The latter is used in the prevention of dental caries.

A sodium fluoride solution, paste or powder, which has been acidulated to pH 3 to 4 and buffered with a phosphate. It is used in the prevention of dental caries.

The predisposition to tooth decay (DENTAL CARIES).

Diagnostic tests conducted in order to measure the increment of active DENTAL CARIES over a period of time.

More From BioPortfolio on "Stopping Cavities Study: Diamine Silver Fluoride"

Advertisement
Quick Search
Advertisement
Advertisement

 

Relevant Topics

Clincial Trials
In a clinical trial or interventional study, participants receive specific interventions according to the research plan or protocol created by the investigators. These interventions may be medical products, such as drugs or devices; procedures; or change...

Pediatrics
Pediatrics is the general medicine of childhood. Because of the developmental processes (psychological and physical) of childhood, the involvement of parents, and the social management of conditions at home and at school, pediatrics is a specialty. With ...

Drug Discovery
Clinical Approvals Clinical Trials Drug Approvals Drug Delivery Drug Discovery Generics Drugs Prescription Drugs In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which drugs are dis...


Searches Linking to this Trial