A Case Control Study of Patients With Diagnosis of Malignant Hyperthermia

2015-09-29 08:08:23 | BioPortfolio


The purpose of the study is to develop methods to identify predictors of Malignant Hyperthermia.


The current study will use the combination of electronic medical records and genomic information in samples of persons who have exhibited signs of Malignant Hyperthermia (MH) or have family history or high risk of MH to see if risk factors can be identified. These will be compared with control samples of children who have been exposed to the same agents which could induce MH, yet showed no signs of the disorder.

Study Design

Observational Model: Case Control, Time Perspective: Retrospective


Malignant Hyperthermia


Cincinnati Children's Hospital Medical Center
United States




Children's Hospital Medical Center, Cincinnati

Results (where available)

View Results


Published on BioPortfolio: 2015-09-29T08:08:23-0400

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Medical and Biotech [MESH] Definitions

Rapid and excessive rise of temperature accompanied by muscular rigidity following general anesthesia.

Presence of fluid in the PLEURAL CAVITY as a complication of malignant disease. Malignant pleural effusions often contain actual malignant cells.

The induction of local hyperthermia by either short radio waves or high-frequency sound waves.

The use of focused short radio waves to produce local hyperthermia in an injured person or diseased body area.

The use of focused, high-frequency sound waves to produce local hyperthermia in certain diseased or injured parts of the body or to destroy the diseased tissue.

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