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Effect of Parecoxib Sodium and Flurbiprofen Injection on Postoperative Shivering

2015-10-08 09:53:24 | BioPortfolio

Summary

Shivering is an early postoperative complication during the postoperative recovery period, and there is no clear consensus about the best way for its prevention. The aim of the study was to compare the efficacy and accompanying side effects of prophylactic flurbiprofen with that of parecoxib or placebo for reducing postoperative shivering.

Description

one hundred forty-five patients with American Society of Anesthesiologists physical status I-II, who were scheduled for colorectal operation under general anesthesia, were randomly assigned to receive flurbiprofen (Group F), parecoxib sodium (Group P ) or normal saline(Group S)40min before the end of surgery. Hemodynamic parameters were monitored. The occurrence of shivering postoperative nausea and vomiting were recorded during the recovery period. And visual analogue score (VAS) and ramsy sedation scale (RSS) were also recorded.

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Treatment

Conditions

Postoperative Shivering

Intervention

parecoxib sodium, flurbiprofen, saline

Location

Anesthesia Department, Tumor Hospital of Guangxi Medical University
Nanning
Guangxi
China
530021

Status

Completed

Source

Guangxi Medical University

Results (where available)

View Results

Links

Published on BioPortfolio: 2015-10-08T09:53:24-0400

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