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In-situ Cytokines Expression in the CNS in Amyotrophic Lateral Sclerosis (ALS)

2015-10-22 13:53:23 | BioPortfolio

Summary

The investigators aim at exploring the differential/topographical in-situ expression of cytokines in the central nervous system (CNS) of patients who died with amyotrophic lateral sclerosis (ALS), using archived histopathology slides and residual paraffin blocks from autopsied cases. Previous studies from the investigators and other groups showed that inflammatory cytokines are implicated in several neurological affections, particularly neurodegenerative conditions. However, in-situ cytokine expression has never been studied so far in ALS. The investigators wanted to see if these neuro-mediators are involved in the neuromolecular chain/cascade underlying ALS.

Study Design

Time Perspective: Retrospective

Conditions

Amyotrophic Lateral Sclerosis

Intervention

in-situ cytokine expression

Location

CHU Brugmann
Brussels
Belgium
1020

Status

Completed

Source

Brugmann University Hospital

Results (where available)

View Results

Links

Published on BioPortfolio: 2015-10-22T13:53:23-0400

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