The Effect of GLP-1 on Postprandial Glucagon Secretion Independent of The Gastric Emptying Rate

2015-10-23 14:08:22 | BioPortfolio


Aim: To investigate the glucagonostatic effect of glucagon-like peptide-1 (GLP-1) independent of the gastric emptying rate.


Aim: To investigate the glucagonostatic effects of glucagon-like peptide-1 (GLP-1) during prolonged and intermittent stimulation of the GLP-1 receptor independent of the gastric emptying rate. Glucagon concentrations will be measured following a liquid meal administered in duodenum at baseline and after exenatide, and liraglutide treatment.

Study Design

Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Treatment


Type 1 Diabetes


Liraglutide, Exenatide, Liquid meal test, No drug (Baseline day)


Enrolling by invitation


Hvidovre University Hospital

Results (where available)

View Results


Published on BioPortfolio: 2015-10-23T14:08:22-0400

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