Intranasal Delivery of Testosterone and Its Effect on Doping Markers

2015-11-22 22:05:23 | BioPortfolio

Published on BioPortfolio: 2015-11-22T22:05:23-0500

Clinical Trials [334 Associated Clinical Trials listed on BioPortfolio]

Diurnal Testosterone Concentration

In this case‐controlled, observational study, 24 subjects will participate in a 12‐hour blood collection with a single blood draw at +24 hours. 12 men will have low testosterone levels...

Generation of Positive Biological Samples to Epoetin for Doping Control.

The study consists of generation of biological samples (in blood and urine) positive to Epoetin alfa for laboratories that wish to perform the analysis of doping controls and maintain accr...

A Study of Fortigel Testosterone Gel 2% in Males With Low Testosterone

Low testosterone is a condition that occurs when the body is unable to produce sufficient quantities of testosterone. The medical name for low testosterone is hypogonadism. Hypogonadism c...

Pharmacokinetic Evaluation of Testosterone Gel (1%)

Measure and evaluate the level of testosterone in blood, and determine the safety and tolerability following daily applications of testosterone gel. Subjects who complete this trial may pa...

Testosterone-Dependent Effects on Protein Biomarkers From Healthy Males

The study is designed to identify and validate new protein biomarkers in blood related to testosterone activity. Thirty healthy young males underwent pharmaceutical castration to lower tes...

PubMed Articles [6989 Associated PubMed Articles listed on BioPortfolio]

Case Study: Absorption of Testosterone Cream via Scrotal Delivery.

Transdermal testosterone has been used for years to treat patients with low testosterone symptoms. Clinically, we have monitored patients to evaluate results of testosterone absorption via blood serum...

Transfer of Topical Testosterone to Subcutaneous Microdialysate, Blood and Saliva in Healthy Young Men.

We evaluated percutaneous penetration of topical testosterone and subsequent transfer to subcutaneous tissue, blood and saliva.

Varicocele Repair Versus Testosterone Therapy for Older Hypogonadal Men with Clinical Varicocele and Low Testosterone.

As men age, serum testosterone levels decrease. This reduction in testosterone levels may cause symptoms leading to hypogonadism. In addition, the presence of a varicocele can impair Leydig cell funct...

The effect of endurance training and testosterone supplementation on the expression of blood spinal cord barrier proteins in rats.

The present study aimed to estimate the effect of endurance training, two doses of testosterone, and the combination of these stimuli on the level of the endothelial proteins claudin, occludin, JAM-1,...

Sport supplement use predicts doping attitudes and likelihood via sport supplement beliefs.

The aim of this study was to examine: 1) whether sport supplement use is related to doping and 2) whether sport supplement beliefs mediated this relationship. In Study 1, athletes (N = 598), complete...

Medical and Biotech [MESH] Definitions

Steroidal compounds related to TESTOSTERONE, the major mammalian male sex hormone. Testosterone congeners include important testosterone precursors in the biosynthetic pathways, metabolites, derivatives, and synthetic steroids with androgenic activities.

A potent androgenic metabolite of TESTOSTERONE. Dihydrotestosterone (DHT) is generated by a 5-alpha reduction of testosterone. Unlike testosterone, DHT cannot be aromatized to ESTRADIOL therefore DHT is considered a pure androgenic steroid.

A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.

An ester of TESTOSTERONE with a propionate substitution at the 17-beta position.

Illegitimate use of drugs for a desired effect in competitive sports; includes humans and animals.

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