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Primary Ovarian Insufficiency, Polycystic Ovary Syndrome & the CardiOvascular Risk Profile

2015-12-01 00:23:23 | BioPortfolio

Summary

The polycystic ovary syndrome (PCOS) is the most common endocrinopathy amongst women of reproductive age. PCOS is associated with various cardiovascular risk factors such as obesity, glucose intolerance, dyslipidemia hypertension and the metabolic syndrome. Whether these increased cardiovascular risk factors result in the development of actual cardiovascular disease in later life remains to be established.

Women with premature ovarian insufficiency (POI), experience menopause prior to the age of 40 years. Women with POI may exhibit dyslipidemia. A young age at menopause has been previously associated with increased cardiovascular morbidity and mortality.

Description

Cardiovascular risk profile will be assessed in women with PCOS and POI > 45 years of age, consisting of:

fasting serum and urine analyses blood pressure, length, weight, waist circumference, hip circumference ECG carotid intima media thickness cardiac ultrasound

spare serum, plasma and urine will be stored in -80 degrees celsius biobank.

Study Design

Observational Model: Case Control, Time Perspective: Cross-Sectional

Conditions

Cardiovascular Diseases

Intervention

cardiovascular screening

Location

University Medical Center Utrecht
Utrecht
Netherlands

Status

Recruiting

Source

UMC Utrecht

Results (where available)

View Results

Links

Published on BioPortfolio: 2015-12-01T00:23:23-0500

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