Copeptin in Normal- to Hyperosmolar States

2016-01-07 10:08:22 | BioPortfolio


Kinetics of Copeptin in response to osmotic alterations in healthy volunteers


Construction of the standard area of copeptin release in the normo- and hyperosmolar state and its half-life based on ist decline during hypoosmotic Suppression in healthy volunteers.

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label


Copeptin Blood Values


Hypertonic saline infusion


University Hospital Würzburg




University Hospital, Basel, Switzerland

Results (where available)

View Results


Published on BioPortfolio: 2016-01-07T10:08:22-0500

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Copeptin and its role in the diagnosis of diabetes insipidus and the syndrome of inappropriate antidiuresis (SIAD).

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Medical and Biotech [MESH] Definitions

Hypertonic sodium chloride solution. A solution having an osmotic pressure greater than that of physiologic salt solution (0.9 g NaCl in 100 ml purified water).

Solutions that have a greater osmotic pressure than a reference solution such as blood, plasma, or interstitial fluid.

The complete summaries of the frequencies of the values or categories of a measurement made on a group of items, a population, or other collection of data. The distribution tells either how many or what proportion of the group was found to have each value (or each range of values) out of all the possible values that the quantitative measure can have.

A genus of HALOBACTERIACEAE distinguished from other genera in the family by the presence of specific derivatives of TGD-2 polar lipids. Haloarcula are found in neutral saline environments such as salt lakes, marine salterns, and saline soils.

Any liquid used to replace blood plasma, usually a saline solution, often with serum albumins, dextrans or other preparations. These substances do not enhance the oxygen- carrying capacity of blood, but merely replace the volume. They are also used to treat dehydration.

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