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Study of Kids Itch Severity (SKIS)

2016-02-03 17:53:24 | BioPortfolio

Summary

This purpose of this study is to validate two measures of chronic itching in kids: itch severity (ItchyQuant) and the impact on their quality of life (ItchyQoL).

Description

There are many diseases that affect children where the primary symptom is pruritus. This study aims to validate an age appropriate pediatric version of the ItchyQoL, a pruritus-specific quality of life instrument, and the ItchyQuant, a self-reported itch severity scale, to better understand how pruritus affects the pediatric population. These instruments will comprehensively capture the severity and impact of pruritus in children. The physicians want to explore the opportunity to integrate patient-reported outcome measures (PROM) as a patient-reported tool in the ambulatory setting.

Study Design

Time Perspective: Prospective

Conditions

Chronic Pruritus

Location

Emory University
Atlanta
Georgia
United States
30322

Status

Enrolling by invitation

Source

Emory University

Results (where available)

View Results

Links

Published on BioPortfolio: 2016-02-03T17:53:24-0500

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Efficacy of Pregabalin in the Management of Chronic Uremic Pruritus

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Does IV Ondansetron Prevent Pruritus After Intrathecal Morphine in Pediatric Patients?

This is a prospective randomized, double-blind, placebo-controlled study to compare the incidence and intensity of ITM-induced pruritus and nausea/vomiting using pre-emptive IV ondansetron...

Klotho in Chronic Kidney Disease-associated Pruritis (CKD-aP)

Studying whether Klotho and FGF23 have a role in UP and whether their expression change by BB-UVB with the improvement of pruritus.

PubMed Articles [6352 Associated PubMed Articles listed on BioPortfolio]

Usability of Validated Sleep-assessment Questionnaires in Patients with Chronic Pruritus: An Interview-based Study.

Impaired sleep due to nocturnal pruritus is a common symptom in patients with chronic pruritus. However, there is no standardized, simplified instrument for assessing sleep-related problems in patient...

Serlopitant for the treatment of chronic pruritus: results of a randomized, multicenter, placebo-controlled phase 2 clinical trial.

The substance P/neurokinin 1 receptor (NKR) pathway is critical in chronic pruritus; anecdotal evidence suggests antagonism of this pathway can reduce chronic itch.

Density of mast cells and intensity of pruritus in psoriasis vulgaris: a cross sectional study.

Psoriasis is a chronic and prevalent disease, and the associated pruritus is a common, difficult-to-control symptom. The mediators involved in psoriatic pruritus have not been fully established.

Are patients with chronic pruritus more susceptible to social stress than healthy controls? An experimental case-control-study.

Previous research suggests associations between stress and pruritus in population samples and in patients with atopic dermatitis (AD) but research is lacking for patients with chronic pruritus (CP) of...

Clinical Characteristics of Pruritus in Systemic Sclerosis Vary According to the Autoimmune Subtype.

Pruritus is a frequent symptom in systemic sclerosis (SSc), with a prevalence of 40-65%, but its pathophysiology is poorly understood. This study investigated the immunological component of pruritus. ...

Medical and Biotech [MESH] Definitions

Intense chronic itching in the anal area.

A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.

A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema.

A subcategory of CHRONIC OBSTRUCTIVE PULMONARY DISEASE. The disease is characterized by hypersecretion of mucus accompanied by a chronic (more than 3 months in 2 consecutive years) productive cough. Infectious agents are a major cause of chronic bronchitis.

A disease of chronic diffuse irreversible airflow obstruction. Subcategories of COPD include CHRONIC BRONCHITIS and PULMONARY EMPHYSEMA.

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Pediatrics
Pediatrics is the general medicine of childhood. Because of the developmental processes (psychological and physical) of childhood, the involvement of parents, and the social management of conditions at home and at school, pediatrics is a specialty. With ...


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