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Use of Hyaluronic Acid as a Therapeutic Strategy for Bone Repair in Human

2016-03-18 04:48:41 | BioPortfolio

Summary

The aim of this study is to evaluate the effects of hyaluronic acid (HA) on bone healing in human dental sockets.

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Conditions

Alveolar Bone Loss

Intervention

hyaluronic acid, Placebo

Status

Completed

Source

Federal University of Minas Gerais

Results (where available)

View Results

Links

Published on BioPortfolio: 2016-03-18T04:48:41-0400

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Medical and Biotech [MESH] Definitions

Resorption or wasting of the tooth-supporting bone (ALVEOLAR PROCESS) in the MAXILLA or MANDIBLE.

Surgical procedure to add bone to the ALVEOLAR RIDGE in children born with a CLEFT LIP and a CLEFT PALATE.

An abnormal congenital condition, associated with defects in the LAMIN TYPE A gene, which is characterized by premature aging in children, where all the changes of cell senescence occur. It is manifested by premature greying; hair loss; hearing loss (DEAFNESS); cataracts (CATARACT); ARTHRITIS; OSTEOPOROSIS; DIABETES MELLITUS; atrophy of subcutaneous fat; skeletal hypoplasia; elevated urinary HYALURONIC ACID; and accelerated ATHEROSCLEROSIS. Many affected individuals develop malignant tumors, especially SARCOMA.

The fibrous CONNECTIVE TISSUE surrounding the TOOTH ROOT, separating it from and attaching it to the alveolar bone (ALVEOLAR PROCESS).

Loss or destruction of periodontal tissue caused by periodontitis or other destructive periodontal diseases or by injury during instrumentation. Attachment refers to the periodontal ligament which attaches to the alveolar bone. It has been hypothesized that treatment of the underlying periodontal disease and the seeding of periodontal ligament cells enable the creating of new attachment.

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