Evaluation of the Irritation Potential of Products in Human Eyes

2016-03-22 06:23:23 | BioPortfolio


To evaluate the human eye irritation potential of one test sunscreen formulation.

Study Design

Allocation: Randomized, Endpoint Classification: Safety Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor)


Sunscreening Agents


Sunscreen lotion SPF (Sun Protection Factor) 50 (BAY987521), Ophthalmic Ointment


St. Petersburg
United States





Results (where available)

View Results


Published on BioPortfolio: 2016-03-22T06:23:23-0400

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A measure of relative protection provided by SUNSCREENING AGENTS against burns due to ultraviolet (UV) radiation from a light source.

A glucocorticoid derivative used topically in the treatment of various skin disorders. It is usually employed as a cream, gel, lotion, or ointment. It has also been used topically in the treatment of inflammatory eye, ear, and nose disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p732)

A sensory branch of the trigeminal (5th cranial) nerve. The ophthalmic nerve carries general afferents from the superficial division of the face including the eyeball, conjunctiva, upper eyelid, upper nose, nasal mucosa, and scalp.

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Protection conferred on a host by inoculation with one strain or component of a microorganism that prevents infection when later challenged with a similar strain. Most commonly the microorganism is a virus.

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