Corneal Biomechanics and Corneal Reshaping Therapy

2016-03-28 08:47:52 | BioPortfolio


The aim of the proposed study is to investigate the predictive value of corneal biomechanical properties in corneal reshaping therapy and the role of these parameters in determining the amount of myopia reduction.


Experiment 1: To evaluate changes in corneal biomechanics caused by short-term corneal reshaping therapy.

Subjects will wear a conventional RGP lens in one eye, randomly selected, and an orthokeratology lens in the fellow eye, for 30 minutes, 60 minutes and one night, respectively. Corneal stiffness and tangent modulus will be measured before and after each wearing period.

Experiment 2: To evaluate changes in and the recovery of corneal biomechanics effected by long-term corneal reshaping and to assess whether corneal biomechanics can predict the rate of corneal reshaping.

Subjects will wear orthokeratology lenses for 6 months. Regular follow up visits (1 week, 1 month, 3 months and 6 months) will be arranged to monitor the changes in corneal stiffness and tangent modulus.

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment




Corneal reshaping therapy


The Hong Kong Polytechnic University
Hong Kong




The Hong Kong Polytechnic University

Results (where available)

View Results


Published on BioPortfolio: 2016-03-28T08:47:52-0400

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