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Nutrition, Overgrowth, and Vaccine Efficacy in Low-income Settings

2016-04-20 18:23:22 | BioPortfolio

Summary

The purpose of this study is to assess the impact of small intestine bacterial overgrowth (SIBO) on childhood nutritional status, growth, and oral vaccine efficacy.

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Conditions

Small Intestine Bacterial Overgrowth

Location

The International Centre for Diarrhoeal Disease Research, Bangladesh
Dhaka
Bangladesh

Status

Recruiting

Source

University of Virginia

Results (where available)

View Results

Links

Published on BioPortfolio: 2016-04-20T18:23:22-0400

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Medical and Biotech [MESH] Definitions

A malabsorption syndrome that is associated with a blind loop in the upper SMALL INTESTINE that is characterized by the lack of peristaltic movement, stasis of INTESTINAL CONTENTS, and the overgrowth of BACTERIA. Such bacterial overgrowth interferes with BILE SALTS action, FATTY ACIDS processing, MICROVILLI integrity, and the ABSORPTION of nutrients such as VITAMIN B12 and FOLIC ACID.

Tumors or cancer in the ILEUM region of the small intestine (INTESTINE, SMALL).

Pathological conditions in the DUODENUM region of the small intestine (INTESTINE, SMALL).

Tumors or cancer in the JEJUNUM region of the small intestine (INTESTINE, SMALL).

A 59 amino acid (6.6 kDa) trefoil factor that contains a single trefoil domain. It is expressed in all tissues with MUCOUS MEMBRANES, including GOBLET CELLS of the SMALL INTESTINE and LARGE INTESTINE. It associates with MUCIN-2 in the small intestine and may regulate epithelial CELL MIGRATION and WOUND HEALING.

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