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The Relationship Between White Matter Hyperintensity With Cognition and Emotion

2016-05-04 21:53:21 | BioPortfolio

Summary

White matter hyperintensity (WMH) has been found to be related with cognitive and emotional dysfunction. A presumed mechanism is that WMH disrupts the structural connectivity within a large-scale brain network, thereby impairing the brain's ability to integrate the neural processes efficiently. It is not yet clear, what the pattern of brain network disruption relates to WMH and how the brain network disruption induced by WMH has an effect on cognition and emotion performance. Using multi-model magnetic resonance imaging (MRI) techniques, we aimed to explore the mechanisms of cognitive decline and depression related with brain network dysfunction in patients with WMH, and to provide objective imaging marker for early diagnosis and prevention of WMH associated cognitive decline and depression.

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Conditions

Aged

Location

The 2nd Affiliated Hospital of Zhejiang University, School of Medicine,
Hangzhou
Zhejiang
China
310009

Status

Recruiting

Source

Zhejiang University

Results (where available)

View Results

Links

Published on BioPortfolio: 2016-05-04T21:53:21-0400

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