Resistant Bacterial Infections in the Early Post LDLT Period

2016-05-20 11:23:22 | BioPortfolio


The purpose of this work was to study the incidence, types, risk factors and causative organisms of bacterial infections in HCV Egyptian patients following Liver Transplantation. Moreover, to identify the emerging resistant strains and their proper antimicrobial therapy


This prospective descriptive study has been done at Tropical Medicine department in the period between January 2013 till May 2014.

After the approval of the scientific and ethical committee of Ain Shams University Hospital, Patients with HCV positive end stage liver disease (ESLD) eligible for liver transplantation in Ain Shams Center for organs transplantation (ASCOT); Ain Shams University, (fulfilling the inclusion criteria) were included in the current study. Thirty five Patients were recruited and each one was followed up during a period of 3months following transplantation.

Included patients were divided into 2 groups:

Group 1 included patients who had a postoperative single episode of infection. Group 2 included those patients who had more than 1 episode of postoperative bacterial infection whom were further evaluated for the presence of emerging strains and/or antibiotic resistance.

Study Design

Observational Model: Cohort, Time Perspective: Prospective


Post LDLT Recurrent,Resistant Bacterial Infections


Living donor liver transplantation




Ain Shams University

Results (where available)

View Results


Published on BioPortfolio: 2016-05-20T11:23:22-0400

Clinical Trials [4861 Associated Clinical Trials listed on BioPortfolio]

Adult-to-Adult Living Donor Liver Transplantation Study

There are two principal purposes of this study: 1) to determine whether it is more beneficial for a liver transplant recipient candidate to pursue a living donor liver transplant (LDLT) o...

Population Pharmacokinetics of Fentanyl in Patients Undergoing Living Donor Liver Transplantation

The aim of this study was to characterize pharmacokinetics of fentanyl during and after Living Donor Liver Transplantation (LDLT), using population pharmacokinetic analysis with non linear...

DCreg in Living Donor Liver Transplantation

Phase I/II, single center, prospective, open-label, non-controlled, non-randomized, interventional, cohort study in which low risk living donor liver transplant (LDLT) recipients will rece...

Orthotopic Liver Transplantation Using a Living Donor

The purpose of this study is to: determine the safety of donor right hepatic lobectomy as a procedure to provide a liver graft for living donor liver transplantation. study the reg...

Antegrade Arterial and Portal Flushing Versus Portal Flushing Only in LDLT

Arterial flushing is a standard recommendation in deceased donor liver transplantation but not in living donor liver transplantation due to the risk of arterial intimal injury and short co...

PubMed Articles [18403 Associated PubMed Articles listed on BioPortfolio]

Genetic polymorphisms of the hepatic pathways of fatty liver disease after living donor liver transplantation.

Fatty liver disease (FLD) is an important complication associated with liver transplantation, and the cytochrome P-450 system of the donor liver may be involved in its pathogenesis. To explore the eff...

Assessing men with erectile dysfunction before and after living donor liver transplantation in real-world practice: Integrating laboratories into clinical settings.

To evaluate the predictive role of the Model for End-Stage Liver Disease (MELD) score concerning changes in testosterone levels following living donor liver transplantation (LDLT) and the effects of L...

Adrenalectomy for solitary recurrent hepatocellular carcinoma five years after living donor liver transplantation: A case report.

The adrenal gland is a rare site for hepatocellular carcinoma (HCC) recurrence after living-donor liver transplantation (LDLT). Solitary adrenal recurrence can be managed by surgical excision, with ex...

Survival following right lobe split graft, living- and deceased-donor liver transplantation in adult patients: a systematic review and network meta-analysis.

Graft and patient survival outcomes following split liver transplantation (SLT), living-donor liver transplantation (LDLT), and deceased-donor liver transplantation (DDLT) were estimated using Bayesia...

Impact of Hepatic Artery Size Mismatch between Donor and Recipient on Outcomes after Living-donor Liver Transplantation using the Right Lobe.

The aim of this study was to evaluate the effect of hepatic artery (HA) size mismatch anastomosis on outcomes after living-donor liver transplantation (LDLT).

Medical and Biotech [MESH] Definitions

An organism that, as a result of transplantation of donor tissue or cells, consists of two or more cell lines descended from at least two zygotes. This state may result in the induction of donor-specific TRANSPLANTATION TOLERANCE.

Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)

An organism whose body contains cell populations of different genotypes as a result of the TRANSPLANTATION of donor cells after sufficient ionizing radiation to destroy the mature recipient's cells which would otherwise reject the donor cells.

Final stage of a liver disease when the liver failure is irreversible and LIVER TRANSPLANTATION is needed.

The transference of a part of or an entire liver from one human or animal to another.

More From BioPortfolio on "Resistant Bacterial Infections in the Early Post LDLT Period"

Quick Search


Relevant Topics

Tropical Medicine
Tropical Medicine is the study of diseases more commonly found in tropical regions than elsewhere. Examples of these diseases are malaria, yellow fever, Chagas disease, Dengue, Helminths, African trypanosomiasis, Leishmaniasis, Leprosy, Lymphatic filaria...

Hepatology is the study of liver, gallbladder, biliary tree, and pancreas, and diseases associated with them. This includes viral hepatitis, alcohol damage, cirrhosis and cancer. As modern lifestyles change, with alcoholism and cancer becoming more promi...

Searches Linking to this Trial