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Influence of Gender Specific Differences of Saliva Composition on the Development of Dental Erosion - an In-situ Study

2016-05-25 12:38:21 | BioPortfolio

Summary

Healthy volunteers are observationally wearing an intraoral device with bovine tooth samples once for two hours. Afterwards, Calcium release from the bovine enamel and dentin samples is measured after extraoral erosion.

Total protein concentration within the formed salivary pellicles on the bovine samples is determined. Further Salivary parameters (unstimulated and stimulated saliva flow rate, pH, buffer capacity, albumin and total protein content as well as concentration of inorganic calcium, phosphate and fluoride) are being measured.

The aim of this study is to investigate whether gender differences in the salivary composition correlate with predisposition to erosion.

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Conditions

Dental Erosion

Intervention

Wearing of an intraoral device with bovine tooth samples

Location

University Medical Center Göttingen, Dept. of Preventive Dentistry, Periodontology and Cariology
Göttingen
Lower Saxony
Germany
37075

Status

Recruiting

Source

University of Göttingen

Results (where available)

View Results

Links

Published on BioPortfolio: 2016-05-25T12:38:21-0400

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Medical and Biotech [MESH] Definitions

The pathologic wearing away of the tooth substance by brushing, bruxism, clenching, and other mechanical causes. It is differentiated from TOOTH ATTRITION in that this type of wearing away is the result of tooth-to-tooth contact, as in mastication, occurring only on the occlusal, incisal, and proximal surfaces. It differs also from TOOTH EROSION, the progressive loss of the hard substance of a tooth by chemical processes not involving bacterial action. (From Jablonski, Dictionary of Dentistry, 1992, p2)

The wearing away of a tooth as a result of tooth-to-tooth contact, as in mastication, occurring only on the occlusal, incisal, and proximal surfaces. It is chiefly associated with aging. It is differentiated from TOOTH ABRASION (the pathologic wearing away of the tooth substance by friction, as brushing, bruxism, clenching, and other mechanical causes) and from TOOTH EROSION (the loss of substance caused by chemical action without bacterial action). (Jablonski, Dictionary of Dentistry, 1992, p86)

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A tooth from which the dental pulp has been removed or is necrotic. (Boucher, Clinical Dental Terminology, 4th ed)

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