Action Selection and Arm Rehabilitation After Stroke

2016-05-31 14:58:18 | BioPortfolio


After stroke, individuals often have persistent difficulty using the arm and hand in everyday functional tasks that reduces quality of life. Currently available rehabilitation techniques are not adequate and new protocols are needed that are based on an understanding of how brain regions work together to produce skilled movement. This research project aims to improve our understanding of how the brain controls movement after stroke and determine whether a period of motor practice that targets specific brain regions through the addition of action selection demands leads to improved arm function. We hypothesize that arm motor function and the ability to efficiently activate the action selection motor circuit during movement will improve after training.


Rehabilitation of arm impairment after stroke includes the repetitive practice of functional tasks. In healthy adults, planning plays a vital role in the control of skilled movement, however, the behavioral and neural correlates of planning have largely been unexplored in individuals recovering from stroke. Action selection is an important motor planning process that engages dorsal premotor cortex (PMd) in controls. While PMd activation is a commonly reported neural correlate of motor recovery after stroke, the role of PMd in action selection and motor training are not known. Therefore, the purpose of this study is to determine the effect of training that includes action selection demands on the behavioral and neural correlates of movement after stroke. Thirty-eight individuals in the chronic phase of stroke will be recruited. After completion of clinical measures of impairment and function, all participants with stroke will complete a motor action selection task and functional MRI followed by arm training. Arm training will consist of three weeks (15 sessions) of arm motor training (1.5 hours per session) that includes action selection demands on movement. Follow-up clinical testing will occur at the end of treatment and three weeks later.

Study Design

Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment




Arm Training with Action Selection


University of South Carolina
South Carolina
United States




University of South Carolina

Results (where available)

View Results


Published on BioPortfolio: 2016-05-31T14:58:18-0400

Clinical Trials [3789 Associated Clinical Trials listed on BioPortfolio]

Trial Using CogWatch for Tea Making Training in Stroke Apraxia and Action Disorganisation Syndrome

Apraxia and action disorganization syndrome after stroke can disrupt activities of daily living (ADL). Occupational therapy has been effective in improving ADL performance, however, inclus...

The Cortical Motor Effects of PNS and AO on Motor Training in Chronic Stroke

This study aimed to investigate if peripheral nerve stimulation (PNS) paired with action observation (AO) would augment motor training in promoting corticomotor excitability for the pareti...

Rapid Movement Therapy for Stroke Rehabilitation

Stroke survivors have higher risks of falling compared to other healthy non-stroke adults. Stroke patients' balance can be trained by Kinect-based training that enable user friendly and in...

Inflammation and Exercise in Stroke

The purpose of this study is to examine the effects of treadmill training on inflammation in the skeletal muscle and adipose tissue, insulin action in the skeletal muscle, and whole body g...

Personalized Antiplatelet Secondary Stroke PRevenTion

This is a descriptive study designed to evaluate the safety and feasibility of a precision medicine approach to antiplatelet selection for secondary stroke prevention.

PubMed Articles [11020 Associated PubMed Articles listed on BioPortfolio]

The effects of action observation training on improving upper limb motor functions in people with stroke: A systematic review and meta-analysis.

Action observation training (AOT) has been used as a new intervention for improving upper limb motor functions in people with stroke. This systematic review and meta-analysis aims to investigate the e...

Acute stroke rehabilitation for gait training with cyborg type robot Hybrid Assistive Limb: A pilot study.

Robot-assisted gait training following acute stroke could allow patients with severe disability to receive a high dosage and intensity of gait training compared with conventional physical therapy (CP)...

Educating Paramedics on the Finger-to-Nose Test Improves Recognition of Posterior Stroke.

Background and Purpose- Emergency medical services (EMS) stroke recognition facilitates rapid care, however, prehospital stroke screening tools rely on signs that are often absent in posterior circula...

Individualizing Training in Swimming: Evidence for Utilizing the Critical Speed and Critical Stroke Rate Concepts.

To monitor physiological, technical, and performance responses to individualized high-intensity interval training (HIIT) prescribed using the critical speed (CS) and critical stroke rate (CSR) concept...

New Insights into Weather and Stroke: Influences of Specific Air Masses and Temperature Changes on Stroke Incidence.

Meteorological factors seem to influence stroke incidence, however, the complex association between weather and stroke remains unclear. Possible explanations from the literature do not categorize into...

Medical and Biotech [MESH] Definitions

The branch of applied psychology concerned with psychological aspects of selection, assignment, training, morale, etc., of Armed Forces personnel.

The branch of applied psychology concerned with the application of psychologic principles and methods to industrial problems including selection and training of workers, working conditions, etc.

Restoration of functions to the maximum degree possible in a person or persons suffering from a stroke.

Individual's expression of desirability or value of one course of action, outcome, or selection in contrast to others.

Financial support for training including both student stipends and loans and training grants to institutions.

More From BioPortfolio on "Action Selection and Arm Rehabilitation After Stroke"

Quick Search

Relevant Topics

Women's Health
Women's Health - key topics include breast cancer, pregnancy, menopause, stroke Follow and track Women's Health News on BioPortfolio: Women's Health News RSS Women'...

Neurology - Central Nervous System (CNS)
Alzheimer's Disease Anesthesia Anxiety Disorders Autism Bipolar Disorders Dementia Epilepsy Multiple Sclerosis (MS) Neurology Pain Parkinson's Disease Sleep Disorders Neurology is the branch of me...

Stroke - Cerebrovascular Disease (CVA)
A stroke is a serious medical condition that occurs when the blood supply to part of the brain is cut off. Strokes are a medical emergency and prompt treatment is essential because the sooner a person receives treatment for a stroke, the less damage is ...

Searches Linking to this Trial