Determination of RAS Mutation Status in Liquid Biopsies in Subjects With RAS Wild-type.PERSEIDA Study

2016-06-07 16:08:21 | BioPortfolio


Analysis of freely circulating DNA in liquid biopsies using the BEAMing method


Analysis of freely circulating DNA in liquid biopsies using the BEAMing method is proposed as a technique that may be useful for analysing the RAS mutation status in different types of cancer. However, first it is necessary to evaluate the concordance between the results obtained in tumour samples and liquid biopsies.

Primary objective

• To evaluate the RAS mutation status at baseline in liquid biopsies in subjects with RAS wild-type metastatic colorectal cancer.

Secondary objectives

- To evaluate the appearance of new RAS mutations using liquid biopsies at the moment of disease progression.

- To evaluate the appearance of new RAS mutations using liquid biopsies prior to radiological documentation of disease progression.

Study Design

Time Perspective: Prospective


RAS Wild Type mCRC


Research Site





Results (where available)

View Results


Published on BioPortfolio: 2016-06-07T16:08:21-0400

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Medical and Biotech [MESH] Definitions

Animals considered to be wild or feral or not adapted for domestic use. It does not include wild animals in zoos for which ANIMALS, ZOO is available.

A genus of the family RETROVIRIDAE with type C morphology, that causes malignant and other diseases in wild birds and domestic fowl.

The type species of ORBIVIRUS causing a serious disease in sheep, especially lambs. It may also infect wild ruminants and other domestic animals.

The type species of the genus MARDIVIRUS in the family HERPESVIRIDAE. It is the etiologic agent of MAREK DISEASE, infecting domestic fowl and wild birds.

An order of insects comprising the chewing lice or biting lice, many of which are parasitic on wild birds and domestic fowl and on wild and domestic mammals. Suborders include Amblycera and Ischnocera.

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