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Fat-Associated Cardiovascular Organ Dysfunction

2016-06-20 18:53:21 | BioPortfolio

Summary

This is an observational study of cardiovascular risk factors and arterial or cardiac function in subjects with overweight or obesity. Subjects must be between 30 and 65 years of age, have a body mass index >27.0 kg/m2 and free from known heart disease and digestive or psychiatric disorders. Study aims include identifying sex-differences in traditional cardiovascular risk factors and structural and functional abnormalities in arteries and the heart in subjects with overweight or obesity, and how this is influenced by physical fitness.

Description

FATCOR is an observational study of women and men with overweight or obesity. In particular prevalences of conventional cardiovascular risk factors and subclinical arterial or cardiac dysfunction are explored. The study aims at identifying sex differences in presence and clustering of cardiovascular risk factors and presence of subclinical cardiovascular organ damage. The influence of physical fitness on these factors will also be assessed. All participants undergo extensive cardiovascular risk factor assessment including oral glucose tolerance test and ambulatory blood pressure recording. Subclinical cardiovascular dysfunction is assessed by carotid and femoral vascular ultrasound, echocardiography and carotid-femoral pulse wave velocity using applanation tonometry. Physical fitness is assessed from peak oxygen uptake during maximal exercise testing on a treadmill.

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Conditions

Overweight

Intervention

There is no intervention

Location

Haukeland University Hospital, Department of Heart Disease
Bergen
Norway
5021

Status

Recruiting

Source

Haukeland University Hospital

Results (where available)

View Results

Links

Published on BioPortfolio: 2016-06-20T18:53:21-0400

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