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A Noninterventional Genotype/Phenotype Study of mGluR Mutations in Children and Adolescents With ADHD

2016-06-23 19:08:22 | BioPortfolio

Summary

This noninterventional study will assess genomic changes in the metabotropic glutamate receptor (mGluR) network in children and adolescents with ADHD.

Description

Male and female subjects 6 to 17 years of age with a primary psychiatric diagnosis of ADHD will be enrolled in this study. The subject and his or her parent/guardian must agree to genotyping to determine whether the subject has disruptive mutations within any of the approximately 274 mGluR-network genes, and complete an interview that will include information about the subject's ADHD history, treatment, and co-morbidities.

Study Design

Observational Model: Case-Only, Time Perspective: Cross-Sectional

Conditions

Attention Deficit Disorder With Hyperactivity

Location

A.I. DuPont Hospital for Children
Wilmington
Delaware
United States
19803

Status

Recruiting

Source

Medgenics, Inc.

Results (where available)

View Results

Links

Published on BioPortfolio: 2016-06-23T19:08:22-0400

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Medical and Biotech [MESH] Definitions

A behavior disorder originating in childhood in which the essential features are signs of developmentally inappropriate inattention, impulsivity, and hyperactivity. Although most individuals have symptoms of both inattention and hyperactivity-impulsivity, one or the other pattern may be predominant. The disorder is more frequent in males than females. Onset is in childhood. Symptoms often attenuate during late adolescence although a minority experience the full complement of symptoms into mid-adulthood. (From DSM-IV)

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