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The Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of UTTR1147A in Participants With Neuropathic Non-Healing Diabetic Foot Ulcers

2016-07-15 01:23:22 | BioPortfolio

Summary

This trial will evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of repeat dosing of UTTR1147A in patients with neuropathic diabetic foot ulcers that do not respond adequately to standard wound care. Patients across multiple sites will be assigned to one of the 4 cohorts (Cohort A, B, C and D) based on the eligibility criteria and randomized to receive subcutaneous (SC) injections of either UTTR1147A or placebo over 12 weeks, in addition to standard wound care.

Study Design

Allocation: Randomized, Endpoint Classification: Safety Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment

Conditions

Neuropathic Diabetic Foot Ulcers

Intervention

Placebo, UTTR1147A

Location

Roma
Lazio
Italy
00128

Status

Recruiting

Source

Genentech, Inc.

Results (where available)

View Results

Links

Published on BioPortfolio: 2016-07-15T01:23:22-0400

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