Postoperative Cognitive Dysfunction After Propofol Anesthesia for Noncardiac Surgery

2016-07-25 02:43:24 | BioPortfolio


Background: Postoperative cognitive dysfunction (POCD) in elderly patients after noncardiac surgery is a common problem.

Therefore,this study was designed to assess POCD after closed-loop coadministration of propofol and remifentanil guided by bispectral index in comparison to intravenous anesthesia in elderly patients undergoing major noncardiac surgery. Methods: After approval of the local ethical committee was obtained, 204 patients (American Society of Anesthesiologists physical status I-III; age, > 55 yr) undergoing surgery (duration, > 1 h) were enrolled into this pospective randomized monocenter study. Patients received anesthesia 3 days after using a neuropsychological test battery.

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Diagnostic


Patients American Society of Anesthesiologists


neuropsychological test battery


Chu Besancon




Centre Hospitalier Universitaire de Besancon

Results (where available)

View Results


Published on BioPortfolio: 2016-07-25T02:43:24-0400

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