Advertisement

Topics

Pediatric Obesity and the Infant Microbiome

2016-07-26 03:08:21 | BioPortfolio

Summary

The impact of breastfeeding on the infant microbiome in vaginally and Cesarean delivered offspring from obese and normal weight mothers.

Description

Design: Normal weight (NW; pre-pregnant BMI <25.0 kg/m2) and obese (Ob; pre-pregnant BMI >30.0 kg/m2) mothers between 36-38 weeks of pregnancy will be recruited from the University of Florida (UF) Health Shands Hospital and stool, blood, urine, body composition and clinical variables will be collected from mother and infant at delivery, 2-weeks, 2-months and 1-year at the UF Clinical Research Center. The study team will recruit equal samples of pregnant mothers in each the following groups (n=25 in each group): 1) NW vaginal deliveries; 2) NW C-section deliveries; 3) Ob vaginal deliveries and 4) Ob C-section deliveries. Infant body composition is the primary outcome and will be monitored via anthropometry. This proposal is requesting funds to collect human milk (HM) samples, measure bioactive compounds in human milk (HM), and test these data for association with the infant gut microbiome within the context of the longitudinal maternal-infant data described above.

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Conditions

Pediatric Obesity

Status

Not yet recruiting

Source

University of Florida

Results (where available)

View Results

Links

Published on BioPortfolio: 2016-07-26T03:08:21-0400

Clinical Trials [1385 Associated Clinical Trials listed on BioPortfolio]

Pediatric Obesity Research Registry

The Pediatric Obesity Research Registry will function to collect and catalog historical and medical chart related clinical data of patients presenting with pediatric obesity and who agree ...

Efficacy of Increasing Physical Activity to Reduce Children's Visceral Fat

The purpose of this trial is to examine whether adding greater physical activity to standard family-based behavioral pediatric obesity treatment decreases the amount of visceral fat among ...

Evaluation of a Family-based Pediatric Obesity Program: TEENS+

Investigators propose to pilot an adolescent obesity intervention, TEENS+, to examine the feasibility of this dietary intervention strategy and preliminary effectiveness of two models of p...

Creating Healthy Environments for Chicago Kids

Pediatric obesity interventions for low-income populations are increasingly delivered in children's homes, which may make treatment more accessible to families and enhance the potency of t...

Improving Pediatric Obesity Practice Using Prompts

This study compares the effectiveness of electronic health record (EHR)-based tools to support the management of pediatric obesity in primary care. Half of clinicians will receive an inter...

PubMed Articles [6186 Associated PubMed Articles listed on BioPortfolio]

Elevated metabolites of acetaminophen in cord blood of children with obesity.

High-throughput metabolomics has been used cross-sectionally to evaluate differential metabolic profiles associated with human obesity.

Identification of Overweight and Obesity in Low-Income Minority Children by Pediatric Providers and Child Characteristics Associated With Underrecognition.

Childhood overweight and obesity remains prevalent. We sought to identify characteristics associated with correct coding of obese and overweight children ages 2-9 years by pediatric primary care provi...

Finding treatable genetic obesity: strategies for success.

Genetic obesity is responsible for up to 7% of severe childhood obesity. Although current Pediatric Endocrine Society guidelines recommend assessment of children with early-onset morbid obesity and hy...

Executive and Reward-Related Function in Pediatric Obesity: A Meta-Analysis.

This study examined the effect of pediatric obesity on executive function and reward-related decision-making, cognitive processes that are relevant to obesogenic behaviors, and evaluated their associa...

Association of FTO rs9939609 with Obesity.

Association of FTO rs9939609 with Obesity Association of FTO rs9939609 with Obesity Association of FTO rs9939609 with Obesity Association of FTO rs9939609 with Obesity Association of FTO rs9939609 wit...

Medical and Biotech [MESH] Definitions

BODY MASS INDEX in children (ages 2-12) and in adolescents (ages 13-18) that is grossly above the recommended cut-off for a specific age and sex. For infants less than 2 years of age, obesity is determined based on standard weight-for-length percentile measures.

Registered nurses with graduate degrees in nursing who provide care to pediatric patients who are acutely or critically ill.

A condition of having excess fat in the abdomen. Abdominal obesity is typically defined as waist circumferences of 40 inches or more in men and 35 inches or more in women. Abdominal obesity raises the risk of developing disorders, such as diabetes, hypertension and METABOLIC SYNDROME X.

The condition of weighing two, three, or more times the ideal weight, so called because it is associated with many serious and life-threatening disorders. In the BODY MASS INDEX, morbid obesity is defined as having a BMI greater than 40.0 kg/m2.

A sub-PHENOTYPE of obese individuals who have a risk for CARDIOVASCULAR DISEASES between that of healthy individuals with normal weight and unhealthy individuals with obesity.

More From BioPortfolio on "Pediatric Obesity and the Infant Microbiome"

Advertisement
Quick Search
Advertisement
Advertisement

 

Relevant Topics

Obesity
Obesity is the condition in which excess fat has accumulated in the body (mostly in subcutaneous tissues). clinical obesity is considered to be present when a person has a BMI of over 30 (Oxford Dictionary of Medicine). It is becoming increasing common i...

Obstetrics and gynaecology
Fertility Menopause Obstetrics & Gynaecology Osteoporosis Women's Health Obstetrics and gynaecology comprises the care of the pregnant woman, her unborn child and the management of diseases specific to women. Most consultant...

Women's Health
Women's Health - key topics include breast cancer, pregnancy, menopause, stroke Follow and track Women's Health News on BioPortfolio: Women's Health News RSS Women'...


Searches Linking to this Trial