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A Double-Blind, Randomized, Placebo Controlled, Clinical Trial of an Antiplaque Chewing Gum (30 mg) - Phase 2 Proof of Concept in a Generally Healthy Patient Population

2016-08-15 09:39:23 | BioPortfolio

Published on BioPortfolio: 2016-08-15T09:39:23-0400

Clinical Trials [656 Associated Clinical Trials listed on BioPortfolio]

Alcohol-free Essential Oils Containing Mouthrinse Efficacy on 3-day Supragingival Plaque Regrowth

The purpose of this study is to evaluate the antiplaque effects of an alcohol-free essential-oil containing mouthrinse - Listerine Zero (LZ) and an alcohol-based essential oils (EO+) mouth...

Double Blind Randomized Placebo Controlled Trial of FOSTRAP Chewing Gum in Patients With CKD and Hyperphosphatemia

The phosphorus content in saliva is increased in chronic kidney disease. We hypothesize that a chewing gum that binds salivary phosphorus would be a novel, effective agent to reduce serum...

Chewing Gum and Gastric Emptying of Water

The aims of this prospective cross over study was to compare the gastric emptying of 250 ml water in fasting volunteers, in two situations : without chewing gum or while chewing gum during...

Chewing Function in Pediatric Neuromuscular Disorders

We aimed to evaluate chewing function (CF) in children with neuromuscular disorders, and investigate reliability of the Karaduman Chewing Performance Scale (KCPS).

Efficacy Evaluation of the Activity of a Cosmetic Product (Topical Use) on Hair Regrowth vs Placebo

Aim of the study is to evaluate clinically and by non-invasive instrumental evaluations the activity on hair regrowth of a topical cosmetic product versus placebo (comparison within subjec...

PubMed Articles [1410 Associated PubMed Articles listed on BioPortfolio]

Xylitol and sorbitol effects on the microbiome of saliva and plaque.

Chewing gum containing xylitol may help prevent caries by reducing levels of mutans streptococci (MS) and lactobacilli in saliva and plaque. Very little is known about other species which are possibly...

Is plaque regrowth inhibited by dentifrice?-A Systematic Review and meta-analysis with trial sequential analysis.

The aim of this systematic review was to establish in studies with human participants the effect of a regular fluoride dentifrice compared to water or saline on dental plaque inhibition.

Chewing gum for 1 h does not change gastric volume in healthy fasting subjects. A prospective observational study.

Perioperative fasting guidelines differ in their approaches to chewing gum in the preoperative period. Current recommendations range from canceling the surgery to proceeding with it. Given this lack o...

Changes in plaque and gingivitis levels after tooth bleaching. A systematic review.

The primary aim of this systematic review was to evaluate the effect of external tooth bleaching products on plaque indices and to compare it to a placebo or a negative control.

Intra-Plaque Vessels on Contrast-Enhanced Ultrasound Sonography Predict Carotid Plaque Histology.

Although the echogenicity of carotid plaques on carotid enhanced ultrasound (CEUS) was reported to correlate with the historological density of intra-plaque neovessels, it is unclear whether the intra...

Medical and Biotech [MESH] Definitions

Endovascular procedure in which atheromatous plaque is excised by a cutting or rotating catheter. It differs from balloon and laser angioplasty procedures which enlarge vessels by dilation but frequently do not remove much plaque. If the plaque is removed by surgical excision under general anesthesia rather than by an endovascular procedure through a catheter, it is called ENDARTERECTOMY.

Chewing gum which contains NICOTINE.

An index which scores the degree of dental plaque accumulation.

Misunderstanding among individuals, frequently research subjects, of scientific methods such as randomization and placebo controls.

Percutaneous transluminal procedure for removing atheromatous plaque from the coronary arteries. Both directional (for removing focal atheromas) and rotational (for removing concentric atheromatous plaque) atherectomy devices have been used.

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