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This project is an exploratory study, based on the hypothesis of involvement of chemokines in hormonal escape of prostate cancers.
The two main objectives are:
- To describe the variations in expression of chemokines in serum and urine level in patients with prostate cancer
- And to study the disease stage and intra-prostatic concentrations of chemokines based on serum and urine concentrations of chemokines before treatment initiation.
These estimates can be used in future trials set up for the management of prostate cancer
Observational Model: Cohort, Time Perspective: Prospective
Blood samples, Urine samples
Published on BioPortfolio: 2016-08-17T10:53:21-0400
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This study is for patients with metastatic prostate cancer receiving radium-223 as their standard of care therapy. The researchers will collect blood and urine samples from patients before...
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Methods or procedures used to obtain samples of URINE.
Testing erythrocytes to determine presence or absence of blood-group antigens, testing of serum to determine the presence or absence of antibodies to these antigens, and selecting biocompatible blood by crossmatching samples from the donor against samples from the recipient. Crossmatching is performed prior to transfusion.
The collecting of fetal blood samples via ultrasound-guided needle aspiration of the blood in the umbilical vein.
Techniques for using whole blood samples collected on filter paper for a variety of clinical laboratory tests.
A glycoprotein that is a kallikrein-like serine proteinase and an esterase, produced by epithelial cells of both normal and malignant prostate tissue. It is an important marker for the diagnosis of prostate cancer.
Biological therapy involves the use of living organisms, substances derived from living organisms, or laboratory-produced versions of such substances to treat disease. Some biological therapies for cancer use vaccines or bacteria to stimulate the body&rs...
Benign Prostatic Hyperplasia (BPH) Erectile Dysfunction Urology Urology is the branch of medicine concerned with the urinary tract and diseases that affect it. Examples include urethritis, urethrostenosis and incontinence. Urology is a su...
Prostate cancer (cancer de prostata) Prostate cancer (cancer de prostata) is a form of cancer that develops in the prostate, a gland in the male reproductive system. Most prostate cancers are slow growing; however, there are cases of aggressive prostat...