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Pharmacokinetics of GS-0976 in Adults With Normal and Impaired Hepatic Function

2016-09-07 16:23:21 | BioPortfolio

Summary

The primary objective of this study is to evaluate the single-dose pharmacokinetics (PK) of GS-0976 in adults with normal hepatic function, and mild, moderate, or severe hepatic impairment.

Study Design

Allocation: Non-Randomized, Endpoint Classification: Pharmacokinetics Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Nonalcoholic Steatohepatitis (NASH)

Intervention

GS-0976

Location

Orlando
Florida
United States

Status

Not yet recruiting

Source

Gilead Sciences

Results (where available)

View Results

Links

Published on BioPortfolio: 2016-09-07T16:23:21-0400

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Medical and Biotech [MESH] Definitions

Cytoplasmic hyaline inclusions in HEPATOCYTES. They are associated with ALCOHOLIC STEATOHEPATITIS and non-alcoholic STEATOHEPATITIS, but are also present in benign and malignant hepatocellular neoplasms, and metabolic, toxic, and chronic cholestatic LIVER DISEASES.

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Hepatology is the study of liver, gallbladder, biliary tree, and pancreas, and diseases associated with them. This includes viral hepatitis, alcohol damage, cirrhosis and cancer. As modern lifestyles change, with alcoholism and cancer becoming more promi...


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