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CyberCycling to Reduce Therapeutic Side Effects and Improve Quality of Life in AYA Cancers

2016-09-27 22:53:21 | BioPortfolio

Summary

Only a few clinical trials evaluating the potential benefits of exercise have been conducted in adolescents and young adults (AYA) with cancer and, no prior studies have evaluated the potential effects of 'cybercycling' (exergaming on a stationary bike) in AYA cancer survivors. Therefore, we aim to conduct a pilot trial to determine feasibility (adherence, user acceptance) and to explore potential effects of a 'cybercycling' exercise program on fitness, body composition, quality of life, sleep and cognition.

Description

Objectives Specific Aim 1: To evaluate the feasibility (adherence; user acceptance: exercise tolerance, enjoyment and motivation) of performing an adaptive, moderate intensity, aerobic exercise program on a 'cybercycle' compared to control (stretching/resistance bands) in adolescent and young adults (AYA) with cancer.

Aim 1 Hypothesis: We hypothesize that AYA with cancer will be able to adhere to and tolerate the moderate intensity cycling program and, patients in the 'cybercycling' exercise program will have greater exercise tolerance, exercise enjoyment and exercise motivation.

(Exploratory) Aim 2: To explore the effects of an adaptive, moderate intensity aerobic exercise program using a 'cybercycle' compared to control (stretching/resistance bands) on changes in fitness, body composition, quality of life (QoL), fatigue, sleep and cognition.

Aim 2 Hypothesis: We hypothesize that patients in the 'cybercycling' program will have greater improvements in fitness, fatigue, QoL, sleep and cognitive test scores as well as greater reductions in body fat and improved maintenance of fat-free mass compared those in the control condition.

Study Design/Overview:

This study is a randomized trial in 20 adolescent and young adult (AYA) cancer survivors (15-30 years old) which will comparing two intervention arms: 1) aerobic exercise on a 'cybercycle' (stationary cycling with exergaming/videogaming); and, 2) a stretching/resistance band 'control' condition.

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Supportive Care

Conditions

Adolescent and Young Adult Cancers

Intervention

CyberCycling, Stretching, Resistance Bands

Location

Case Medical Center, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center
Cleveland
Ohio
United States
44106

Status

Not yet recruiting

Source

Case Comprehensive Cancer Center

Results (where available)

View Results

Links

Published on BioPortfolio: 2016-09-27T22:53:21-0400

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Medical and Biotech [MESH] Definitions

A type of strength-building exercise program that requires the body muscle to exert a force against some form of resistance, such as weight, stretch bands, water, or immovable objects. Resistance exercise is a combination of static and dynamic contractions involving shortening and lengthening of skeletal muscles.

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A diminution of the skeletal muscle tone marked by a diminished resistance to passive stretching.

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