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Therapeutic Effects of Hydrogen on Steroid-refractory/or Steroid-dependent cGVHD

2016-09-28 23:08:21 | BioPortfolio

Summary

This study suggested that hydrogen has a potential as an effective and safe therapeutic agent on cGVHD.

Description

The investigators will evaluate clinical response rate, time to treatment Failure (TTF), overall survival (OS), and toxicity in cGVHD patients.

Study Design

Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Chronic Graft-versus-host Disease

Intervention

Hydrogen

Location

Navy General Hospital
Beijing
Beijing
China
100048

Status

Recruiting

Source

Navy General Hospital, Beijing

Results (where available)

View Results

Links

Published on BioPortfolio: 2016-09-28T23:08:21-0400

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Medical and Biotech [MESH] Definitions

An immunological attack mounted by a graft against the host because of tissue incompatibility when immunologically competent cells are transplanted to an immunologically incompetent host; the resulting clinical picture is that of GRAFT VS HOST DISEASE.

The clinical entity characterized by anorexia, diarrhea, loss of hair, leukopenia, thrombocytopenia, growth retardation, and eventual death brought about by the GRAFT VS HOST REACTION.

The immune responses of a host to a graft. A specific response is GRAFT REJECTION.

The survival of a graft in a host, the factors responsible for the survival and the changes occurring within the graft during growth in the host.

Manipulation of the host's immune system in treatment of disease. It includes both active and passive immunization as well as immunosuppressive therapy to prevent graft rejection.

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