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Concurrent Chemotherapy Based on Genetic Testing in Patients With High-Risk Salivary Gland Tumors

2016-10-03 23:38:21 | BioPortfolio

Summary

The role of postoperative concurrent chemotherapy (CCT) has not been established for salivary gland tumors (SGTs). This prospective study was conducted to evaluate the feasibility and safety of customized CCT regimens based on the gene targets of SGTs.

Study Design

Allocation: Non-Randomized, Endpoint Classification: Safety Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Salivary Gland Tumors

Intervention

Docetaxel, Intensity-modulated radiotherapy, Pemetrexed, Cisplatin

Location

Shanghai ninth people's hospital
Shanghai
Shanghai
China
200011

Status

Recruiting

Source

Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University

Results (where available)

View Results

Links

Published on BioPortfolio: 2016-10-03T23:38:21-0400

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Medical and Biotech [MESH] Definitions

CONFORMAL RADIOTHERAPY that combines several intensity-modulated beams to provide improved dose homogeneity and highly conformal dose distributions.

Calculi occurring in a salivary gland. Most salivary gland calculi occur in the submandibular gland, but can also occur in the parotid gland and in the sublingual and minor salivary glands.

Glands that secrete SALIVA in the MOUTH. There are three pairs of salivary glands (PAROTID GLAND; SUBLINGUAL GLAND; SUBMANDIBULAR GLAND).

A fistula between a salivary duct or gland and the cutaneous surface of the oral cavity.

A benign, slow-growing tumor, most commonly of the salivary gland, occurring as a small, painless, firm nodule, usually of the parotid gland, but also found in any major or accessory salivary gland anywhere in the oral cavity. It is most often seen in women in the fifth decade. Histologically, the tumor presents a variety of cells: cuboidal, columnar, and squamous cells, showing all forms of epithelial growth. (Dorland, 27th ed)

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Bioinformatics is the application of computer software and hardware to the management of biological data to create useful information. Computers are used to gather, store, analyze and integrate biological and genetic information which can then be applied...


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